| | CHEST: Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff Lecture - Thomas L. ... (Site not responding. Last check: 2007-10-21) |
 | | The presence of an element of vasoconstriction can be deduced from the acute vasodilatation achieved in a minority of primary pulmonary hypertension patients by calcium channel blockers, nitric oxide, prostacyclin, or adenosine. |
 | | It is thought that, at an early stage of the disease, vasoconstriction may be the principal abnormality. |
 | | Hypoxic pulmonary vasoconstriction can be demonstrated in isolated pulmonary vascular smooth muscle cells[4] and consequently, the single smooth muscle cell is a simple model of pulmonary vasoconstriction that has been studied extensively. |
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