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Topic: Vernon Mountcastle


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In the News (Wed 10 Feb 10)

  
  Vernon Mountcastle - Wikipedia, the free encyclopedia
Vernon Mountcastle was a neuroscientist from Johns Hopkins University.
Mountcastle's devotion to studies of single unit neural coding evolved through his leadership in the Bard Labs of Neurophysiology at Johns Hopkins, which was for many years was the only institute in the world devoted to this sub-field, and its work is continued today in the Krieger Mind/Brain Institute.
Vernon Mountcastle (1978), "An Organizing Principle for Cerebral Function: The Unit Model and the Distributed System", The Mindful Brain (Gerald M. Edelman and Vernon B. Mountcastle, eds.) Cambridge, MA: MIT Press.
en.wikipedia.org /wiki/Vernon_Mountcastle   (248 words)

  
 The Johns Hopkins Gazette: April 20, 1998
Vernon Mountcastle, professor emeritus of neuroscience, will receive the National Academy of Sciences' Award in the Neurosciences, given every three years for extraordinary achievement in the field.
Mountcastle returned to Hopkins as a postdoctoral fellow in 1946 and never left.
Mountcastle was director of the Department of Physiology at the School of Medicine from 1964 to 1980, when he founded the Philip Bard Laboratories of Neurophysiology, which were incorporated into the Department of Neuroscience.
www.jhu.edu /~gazette/aprjun98/apr2098/20mount.html   (1396 words)

  
 A narrow-minded master - Nature Neuroscience
Early in his career, Mountcastle began a sustained attack on the somesthetic system from receptor to cortex and was one of the first to combine sophisticated psychophysical methods with single-neuron recording in monkeys.
Mountcastle's book is idiosyncratic not only in what it omits but in what it attacks and what it advocates.
Mountcastle then admits "what those constructive and correlative properties are and how they arise remain unclear." Despite this understandable puzzlement, Mountcastle persists in using "re-entry" as a magic wand to explain cortical function.
www.nature.com /neuro/journal/v2/n5/full/nn0599_399.html   (1009 words)

  
 Harvard University Press/Perceptual Neuroscience/Reviews   (Site not responding. Last check: 2007-11-03)
Vernon B. Mountcastle, M.D. is University Professor of Neuroscience, Emeritus, at the Zanvyl Krieger Mind/Brain Institute of The Johns Hopkins University and winner of the 1998 National Academy of Sciences Award in Neurosciences, in recognition of his "extraordinary contributions to progress in the fields of neuroscience."
Vernon Mountcastle provided the first evidence for the columnar organization of the neocortex by making systematic recordings from single neurons in the somatosensory cortex, which was a tour de force for its time (mid-1950s).
Vernon Mountcastle has written a magnificent overview of our present understanding of perception and the cerebral cortex.
www.hup.harvard.edu /reviews/MOUPER_R.html   (720 words)

  
 The Lasker Foundation | Former Award Winners, Basic Medical Research 1983
Dr. Mountcastle and his colleagues found that the nerve cells of the sensory cortex are arranged in vertical columns, extending from the surface of the cortex down to its depths.
As part of this research, Dr. Mountcastle went on from this pioneering step to clarify the roles of various portions of the brain and sensory integration so as to trace every step in the neural coding of sensation from skin to its final target in the cerebral cortex.
To Dr. Mountcastle, for his profoundly original discoveries which illuminator the brain's ability to perceive and organize information, and to translate sensory impulses into behavior, this 1983 Albert Lasker Basic Medical Research Award is given.
www.laskerfoundation.org /awards/library/1983basic.shtml   (591 words)

  
 Perceptual Neuroscience : The Cerebral Cortex by Vernon B. Mountcastle 0674661885 - Direct Textbook Details and Reviews   (Site not responding. Last check: 2007-11-03)
Vernon Mountcastle has gathered information from a vast number of sources reaching back through two centuries, from phylogenetic, comparative, and neuroanatomical studies of the neocortex to rhythmicity and synchronization in neocortical networks and inquiries into the binding problem.
Mountcastle's language is lucid and scholastic, and discoveries are always given within their historical framework.
Mountcastle provides no direct answer to the question of what the intrinsic function of the cortex is, but promotes its exploration from a dynamic systems stance, with a view to determining how "a distributed system highlights the dynamic neural representation of one, rather than another, sensory event".
www.directtextbook.com /reviews/0674661885   (1464 words)

  
 New Page 2   (Site not responding. Last check: 2007-11-03)
Vernon Mountcastle, a resident of Monkton, Md., was one of 27 Sigma Chi alumni honored as Significant Sigs for 2002.
This honor is given annually in recognition of those who have brought honor and prestige to the name of the Sigma Chi Fraternity through their professional endeavors.
Dr Vernon Mountcastle '38 joins Dr Charles Jacob Smith '01, Stuart Saunders '30, and Dr Carl Gottschalk '42 as Tau brothers who have been recognized as Significant Sigs.
clubs.roanoke.edu /sigmachi/DrMountcastle-SigSig.htm   (205 words)

  
 Mindful Brain - The MIT Press
Mountcastle's paper reviews what is known about the actual structure of various parts of the neo cortex.
There are strong conceptual parallels between Mountcastle's idea of cortical columns and their functional subunits and Edelman's concept of populations of neurons functioning as processors in a brain system based on selectional rather than instructional principles.
"Mountcastle, dean of American neurophysiologists, presents the case for a modular structure of the cerebral cortex....
mitpress.mit.edu /catalog/item?ttype=2&tid=7535   (360 words)

  
 Harvard University Press/The Sensory Hand
Vernon Mountcastle has devoted his career to studying the neurophysiology of sensation--the extended sensory surface, consisting of skin and subcutaneous tissue--in the hand.
In The Sensory Hand Mountcastle provides an astonishingly comprehensive account of the neural underpinnings of the rich and complex tactile experiences evoked by stimulation of the hand.
Mountcastle focuses attention on the nerve pathways linking the hand to central neural structures, structures that play a role in several other aspects of somatic sensation.
www.hup.harvard.edu /catalog/MOUSEN.html   (265 words)

  
 Written Voices Radio
Therefore, Mountcastle argues, all regions of the cortex are performing the same operation.
In fact, Mountcastle argues that the reason one region of cortex looks slightly different from another is because of what it is connected to, and not because its basic function is different.
Mountcastle says they aren't the same, but the way the cortex processes signals from the ear is the same as the way it processes signals from the eyes.
www.writtenvoices.com /titlepageexcerpt.asp?ISBN=0805074562   (1206 words)

  
 Once Unknown, Mountcastle Is Turning Heads Now :: Former walk-on has been a consistent contributor all season for the ...
But Nancy and her parents switched to golf when Vernon Mountcastle came back from his injury, a decision that is paying dividends now for the Wolfpack women's golf team.
Mountcastle grew up at Treyburn Country Club in Durham and attended Durham Academy, which does not field a girls golf team.
Technically, Mountcastle came to NC State as a walk-on because there were no scholarships available.
www.cstv.com /sports/w-golf/stories/050505aab.html   (593 words)

  
 Memorial to Kenneth O. Johnson, PhD.
The method of single unit recording was in its infancy and with Vernon Mountcastle, who was Ken's thesis advisor at Hopkins, Ken decided to study the neural basis of behavior.
Vernon had shown that the neural mechanisms underlying behavior could be studied directly and he had pioneered a new approach of studying the brain by combining psychophysical studies in humans with neurophysiological studies in non-human primates.
Dr. Johnson, who lived in Baltimore near the Homewood campus, was a professor of neuroscience and biomedical engineering, as well as director of the university's Zanvyl Krieger Mind/Brain Institute, which studies the neural mechanisms of higher brain functions.
mind-brain.com /KOJ.asp   (2620 words)

  
 Citations: An organizing principle for cerebral function: the unit module and the distributed system - Mountcastle ...   (Site not responding. Last check: 2007-11-03)
Mountcastle, "An Organizing Principle for Cerebral Function: The Unit Module and the Distributed System," in The Mindful Brain, G. Edelman and V. Mountcastle, Eds., Cambidge: MIT Press, 1978, pp.
Mountcastle, Vernon B. An organizing principle for cerebral function: The unit module and the distributed system.
Mountcastle, An organizing principle for cerebral function: The unit module and the distributed system, In: G. Edelman & V.B. Mountcastle (Eds.), The Mindful Brain, Cambridge, MA: MIT Press, 1978.
citeseer.ist.psu.edu /context/225464/0   (2080 words)

  
 Faculty of Medicine Memorial Minute: Elwood Henneman
This Institute, under the leadership of Wilder Penfield, was a center for research on the localization of function in the cerebral cortex and it was therefore natural for Dr. Henneman to seek postdoctoral training in central nervous system physiology in Professor Bard's department at the Johns Hopkins.
After serving in the Navy as neurosurgeon in the Pacific Theater during WW II he returned to Bard's department; in collaboration with Vernon Mountcastle he undertook an investigation of localization of electrical potentials in the brain evoked by sensory afferents.
In experiments on cats and monkeys he and Mountcastle showed that the tactile surface of the body is represented in the ventro-lateral thalamus by a three dimensional "figurine" of the body.
www.news.harvard.edu /gazette/1998/09.17/FacultyofMedici.html   (1538 words)

  
 Active Skim View of: 7 From Perception to Attention
Mountcastle, who studies the brain's means of spatial perception, has gathered evidence from numerous research projects that the parietal lobe forms part of a complex distributed system by which the brain actually “constructs” reality.
Electrical recordings from single cells have enabled Mountcastle and his colleagues to work out the pattern by which parietal visual neurons are organized—a pattern quite different from that of the visual cortex itself.
In the parietal lobe, a visual neuron will respond, within its receptive field, to a light moving in any of several directions—depending on whether the light is moving toward or away from the center of the field.
www.nap.edu /nap-cgi/skimit.cgi?isbn=0309045290&chap=104-122   (1243 words)

  
 [No title]
The concept of modular functional organization was later expanded upon by the physiologist Vernon B.
Mountcastle, who obtained the first evidence for columnar function through his investigations of the primate somatosensory system, and offered this as a general principle of cortical organization (Mountcastle 1957).
Mountcastle did not obtain any evidence for 'columnar function'.
human-brain.org /mitecs.html   (11732 words)

  
 Welcome to Adobe GoLive 4
Vernon B. Brooks was a pioneer in studies of the neural basis of motor control.
The period from ‘55 on was one of important discoveries about the sensory and motor cortex, notably by Vernon Mountcastle and Charles Phillips with both of whom I had begun to correspond before moving to New York.
In ‘55 Mountcastle's first notes had appeared about peripheral receptive fields of neurons in radially oriented columns in cat's primary sensory cortex and he was about to submit the papers of which he had sent me manuscript copies.
publish.uwo.ca /~brooks/history3.html   (16484 words)

  
 Johns Hopkins Medicine--Neurology Residency Program
I was quite surprised when I received a call from Vernon Mountcastle telling me that Hopkins had selected me to lead the department.
Hopkins has a long tradition of great strength in the basic neurosciences going back to Phil Bard, Vernon Mountcastle, as well as David Bodian and the development of the Neuroscience Department by Sol Snyder and the Hughes Investigators, such as Rick Huganir.
People like Victor McKusick, Vernon Mountcastle, Dan Nathans, Sol Snyder, and Paul Talalay have been extraordinarily supportive of the institution, way beyond just their own research interests or the interests of their departments.
www.neuro.jhmi.edu /nrotrn/1969-1989.html   (3105 words)

  
 Johns Hopkins Magazine -- April 2000
In the mid-1980s, a group of men at Hopkins led by Steven Muller, then president, and Vernon Mountcastle, now professor emeritus of neuroscience, met to discuss the accelerating breakthroughs in the study of the brain.
Recalls Mountcastle, who has done seminal research on higher-function neurons and the modular grouping of brain cells, "It started on a day when Steve Muller had one of his get-togethers out at the Evergreen House.
I described what I thought would be an ideal solution." Mountcastle's ideal solution was a new interdisciplinary research center: the Mind/Brain Institute.
www.jhu.edu /~jhumag/0400web/44.html   (1203 words)

  
 Neocortical Modularity And The Cell Minicolumn   (Site not responding. Last check: 2007-11-03)
Vernon B. Mountcastle: A Life that Transformed the Neurosciences
The Verticality Index: A Quantitative Approach to the Analysis of the Columnar Arrangement of Neurons in the Primate Neocortex
Mountcastle Principle of Columnar Cortex as Basis for Theory of Higher Brain Function Clinical Relevance
www.booksmatter.com /b1594543011.htm   (70 words)

  
 Table of contents for Neocortical modularity and the cell minicolumn   (Site not responding. Last check: 2007-11-03)
Scientific Achievements (Vernon B. Mountcastle and Juan Trippe II, University of Louisville) Chapter 3.
The Verticality Index: A Quantitative Approach to the Analysis of the Columnar Arrangement of Neurons in the Primate Neocortex (Axel Schleicher and Karl Zilles, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany) Chapter 11.
Mountcastle Principle of Columnar Cortex as a Basis for the Theory of Higher Brain Function: Clinical Relevance (Gordon L. Shaw and Mark Bodner, M.I.N.D. Institute) Index.
www.loc.gov /catdir/toc/ecip057/2005002276.html   (290 words)

  
 Krieg Cortical Kudos 2000 -- Azmitia 10 (8): 826 -- Cerebral Cortex   (Site not responding. Last check: 2007-11-03)
Vernon B. Mountcastle is Professor in the Zanvyl Krieger Mind/Brain
Vernon B. Mountcastle was born on July 15, 1918 in the small town
From left to right: Vernon Mountcastle, Catherine Woolley, Nenad Sestan and William Bocking.
cercor.oxfordjournals.org /cgi/content/full/10/8/826   (2028 words)

  
 langbrain: Information Sources
See also the important book by Vernon Mountcastle.
Some of the best evidence for the locations of the various linguistic subsystems comes from the study of brain-damaged patients.
Mountcastle, Vernon B, Perceptual Neuroscience: The Cerebral Cortex.
www.ruf.rice.edu /~lngbrain/rd.htm   (549 words)

  
 Adam Ash: Tacit knowledge and cortical alghorithms
Written by PalmPilot and Treo architect Jeff Hawkins (with the help of science writer Sandra Blakeslee), this 2004 book chronicles Hawkins' shadow career as a neuroscientist searching for a unified theory of the neocortex.
The model he proposes was inspired by the work of Vernon Mountcastle, whose 1978 paper An Organizing Principle for Cerebral Function provided Hawkins with this central insight:
Mountcastle points out that the neocortex is remarkably uniform in appearance and structure.
adamash.blogspot.com /2005/08/tacit-knowledge-and-cortical.html   (791 words)

  
 Colleges.com, college search, undergraduate search
The school adds that its location offers a small city setting with proximity to both the Appalachian Trail and the greater metropolitan area of the Roanoke Valley.
Henry Fowler, former Secretary of U.S. Treasury; Rick Boucher, congressman; Dr. Vernon Mountcastle,
List of graduate schools most often selected by recent graduates: James Madison U, Virginia Commonwealth U, Virginia Polytech Inst and St U, U of Virginia.
www.colleges.com /admissions/collegesearch/college_search.taf?_function=detail&Type=4&school_id=2600101   (170 words)

  
 Brain Cell "Chorus" Appears As Attention Increases   (Site not responding. Last check: 2007-11-03)
Tasks included identifying which of three white squares of light on a video monitor was beginning to dim, and comparing the shape of raised letters or figures pressed against a finger.
Applying a technique perfected by Hopkins neuroscientist Vernon Mountcastle, researchers used seven electrodes to simultaneously monitor individual brain cell activity in the monkeys as they worked.
They originally analyzed the data they gathered for changes in the firing rate of brain cells as the animals switched attention between tasks.
www.sciencedaily.com /releases/2000/03/000308112357.htm   (1025 words)

  
 Untitled
To test the hypothesis, we may consider the properties of cortical columns, descriptions of cortical cells, and how the structure and connectivity of columns correspond (or fail to correspond) to the requirements of the model.
Their shape is quasi-hexagonal, because each cortical column is typically surrounded by six other columns.
"A cortical column is a complex processing and distributing unit that links a number of inputs to a number of outputs via overlapping internal processing chains" (Mountcastle, 1998).
www.ruf.rice.edu /~lngbrain/Sidhya   (1097 words)

  
 M.R. Bauer Foundation at Brandeis
Home > M.R. Bauer Foundation > 1998 Summary Report > Vernon Mountcastle, Ph.D. Vernon Mountcastle, Ph.D. Krieger Mind/Brain Institute
A major research program in neuroscience is to determine the relations between the material order of the world around us and the sensory-perceptual order of our experience; and, to discover the central neural mechanisms of these transformations.
The lecture closed with some speculations about the methods that may be of value in studies of these problems.
www.bio.brandeis.edu /bauer/1998/mountcastle.html   (379 words)

  
 Interhemispheric Relations and Cerebral Dominance - MOUNTCASTLE, VERNON B., ED   (Site not responding. Last check: 2007-11-03)
Interhemispheric Relations and Cerebral Dominance - MOUNTCASTLE, VERNON B., ED
MOUNTCASTLE, VERNON B., ED Interhemispheric Relations and Cerebral Dominance
They offer full satisfaction and normal prices - no markups, no hidden costs, no overcharged shipping costs.
www.antiqbook.com /boox/gac/017847.shtml   (87 words)

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