| | Endotext.com - Endocrinology Of Male Reproduction, Cryptorchidism and Hypospadias (Site not responding. Last check: ) |
 | | In 1974 a rare autosomal form of male pseudohermaphroditism was described in 2 families; one from Dallas (175), and one from the Dominican Republic (176), in these cases, the underlying defect was shown to be a deficiency in the conversion of testosterone to its more active metabolite, dihydrotestosterone. |
 | | Three cases adopted children and in one case in vitro fertilization using the patient's sperm cells resulted in twin siblings, a boy and a girl whose paternity was confirmed by microsatellite studies (184). |
 | | A timing defect leading to lack of testosterone secretion at the critical period in which the virilization of the genitalia occurs can cause male pseudohermaphroditism, however, this is impossible to determine later in postnatal life with the methods available today. |
| www.endotext.org /pediatrics/pediatrics11/pediatrics11_2.htm (5393 words) |