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Topic: Virius Lupus

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	Dictionary of Greek and Roman Biography and Mythology, page 841 (v. 2)
		Lupus is now generally supposed to have been the son of P. Rutilius Lupus, mentioned above.
		LUPUS, VI'RIUS, governor of Britain in the reign of the emperor Alexander Severus, was obliged to purchase peace of the Maeatae, a people bordering upon the Caledonians.
		The name of Virius Lupus frequently occurs in inscriptions found in various.parts of Britain.
	www.ancientlibrary.com /smith-bio/1949.html (848 words)

	Lupus Erythematosus
		Lupus is a member of the group of diseases called "collagen diseases," which include also rheumatoid arthritis, dermatomyositis, and others.
		Lupus is more common in women in the childbearing age, and strikes all races and all geographic areas, no preferences having been noted.
		Lupus and the hydralazine syndrome in man may be related to manganese deficiency.
	www.ucheepines.org /lupus_erythematosus.htm (1463 words)

	Lupus site (SLE)- information on lupus
		Lupus is a chronic (long-lasting) autoimmune disease where the immune system, for unknown reasons, becomes hyperactive and attacks normal tissue.
		Lupus patients can be diagnosed and treated by a number of different specialists, or indeed a combination which could include- rheumatologist, dermatologist, nephrologist, immunologist, or they can just be treated by their GP.
		Lupus does vary in intensity and degree, and there are people who have a mild case, there are those who have a moderate case and there are some who have a severe case (severe organ involvement), which tends to be more difficult to treat and bring under control.
	www.uklupus.co.uk /new.html (2180 words)

	lupus -- eCureMe.com
		Lupus often starts with a fever of unknown cause which lasts for days, weeks or months.
		Lupus has been seen to occur in families, the disease involving parents and children or a child and siblings.
		In directing treatment to lupus, we aim at all three of the currently considered possible causes, a toxicity, an autoimmune or allergic type of reaction, and a viral infection.
	www.ecureme.com /emyhealth/natural/n_lupus.asp (1481 words)

	wolf.html
		In the 1950s, before steroids were discovered and used in lupus treatment, the three-year survival rate was closer to 30 percent, because patients died as their organs deteriorated from uncontrolled inflammation and damage.
		Many systemic lupus patients say there are subtle daily reminders that all is not perfect for them, even in periods of remission-they have days of extreme fatigue, for example, or pains that appear and disappear with no seeming cause.
		Lupus is not a 'life sentence,'" since most people go into extended periods of remission and, thanks to improved therapies, individuals with lupus are living normal life spans.
	www.usc.edu /hsc/info/pr/hmm/98winter/wolf.html (1911 words)

	Lupus
		Lupus can cause a number of lung problems, the most common of which is pleurisy, an inflammation of the chest cavity lining that can produce sharp, stabbing chest pain.
		Lupus is an autoimmune disease, which means that instead of just attacking foreign substances, such as bacteria and viruses, the immune system also turns against healthy tissue.
		Lupus can cause serious kidney damage, and kidney failure is one of the leading causes of death among people with lupus.
	www.cnn.com /HEALTH/library/DS/00115.html (4262 words)

	The Disease Lupus -- Recommendations and Resources (Site not responding. Last check: 2007-11-06)
		Lupus is a bit mysterious, perhaps due to its scant presence in the population.
		Lupus anticoagulant is an autoimmune disorder caused by antibodies that bind to phospholipids and proteins associated with the cell membrane.
		Although it is named "lupus" anticoagulant, most patients with the antibody do not have lupus erythematosus, and only a small proportion will proceed to develop this disease (which causes joint pains, skin problems and renal failure, amongst other complications).
	www.becomingapediatrician.com /health/146/the-disease-lupus.html (1284 words)

	VIRIUS LUPUS (Site not responding. Last check: 2007-11-06)
		"Inasmuch as the Caledonii¹ did not abide by their promises and had made ready to aid the Maeatae,²; and in view of the fact that Severus at the time was devoting himself to the neighbouring war,² Lupus was to purchase peace from the Maeatae for a large sum; and he received a few captives."
		This statement is probably in reference to the continued conflicts in Gaul against factions loyal to the renegade Albinus.
		"For the Goddess Fortune, Virius Lupus, legate of the emperor with pro-praetorian power, the baths having been destroyed by fire, were restored by the First Cohort of Thracians under the direction of Valerius Fronto, cavalry prefect of the Vettonian Wing"
	www.roman-britain.org /people/lupus.htm (265 words)

	LUPUS FOUNDATION OF AMERICA
		Lupus is a chronic inflammatory disease that can affect various parts of the body, especially the skin, joints, blood, and kidneys.
		While lupus can affect the lungs in many ways, pleuritis (pleurisy) is the most common pulmonary manifestation.
		As lupus activity generates immune complexes, they initiate an inflammatory response at this membrane, a condition called pleuritis.
	www.lupus.org /webmodules/webarticlesnet/templates/new_about.aspx?a=291&z=2&page=4 (324 words)

	Virius Lupus Information
		Virius Lupus was a Roman soldier and politician of the late second and early 3rd century.
		Fearful that they would ally with the Caledonian Confederacy and unable to secure troop reinforcements from Severus, Lupus had no choice but to pay the rebels in return for their withdrawal and the return of a few prisoners.
		Lupus slowly restored the forts in the Pennines to Roman control although Hadrian's Wall was not rebuilt until c.
	www.bookrags.com /wiki/Virius_Lupus (252 words)

	Lupus: Risk factors - MayoClinic.com
		Women account for the vast majority of lupus cases and are approximately nine times as likely to develop the disease as men are.
		Although lupus affects people of all ages, including infants and children, it's most often diagnosed between the ages of 15 and 45.
		Lupus sometimes shows up for the first time during pregnancy or shortly after giving birth.
	www.mayoclinic.com /health/lupus/DS00115/DSECTION=4 (328 words)

	MUSC Study Links Lupus and Epstein-Barr Virus
		Although the specific cause of lupus is not yet known, both genetic and environmental triggers are likely involved.
		Among both lupus patients and controls, African Americans had a higher prevalence of EBV-IgG antibodies than white subjects, the telltale sign of a history of EBV infection.
		Among lupus patients, both African-American and white, researchers also observed a genetic variation in CTLA-4, a protein that works on T cells in regulating immunity, and which significantly increased the risk of lupus associated with EBV-IgA antibodies.
	www.musc.edu /pr/lupus.htm (588 words)

	CNN - Study links lupus to Epstein Barr virus - December 15, 1997
		Although the cause of lupus remains unknown, a new study suggests that there may be a link between it and the Epstein Barr virus, which causes mononucleosis.
		Researchers found 99 percent of the young lupus patients they studied tested positive for the Epstein Barr virus, compared to 70 percent of those without lupus.
		Lupus is three times more common in African American women, and the group at greatest risk is African Caribbean women.
	www.cnn.com /HEALTH/9712/15/lupus.discovery (382 words)

	Lupus
		Lupus is a disease in which the body's own defenses are turned against themselves.
		While lupus itself is not inherited, it is possible that some combinations of genes make a person more likely to develop the condition.
		Lupus may not be a major illness, or it can be a serious, life-threatening one.
	www.csmc.edu /pf_5567.html (1331 words)

	An Increased Prevalence of Epstein-Barr Virus Infection in Young Patients Suggests a Possible Etiology for Systemic ...
		of the spliceosome in lupus reflect an etiology of lupus.
		Sera from lupus patients (cases) or their controls were tested for IgG anti-EBV-VCA antibodies and standardized for seroconversion.
		Sera from lupus patients (cases) or their controls were tested for IgG antiviral antibodies and standardized for seroconversion.
	www.jci.org /cgi/content/full/100/12/3019 (6083 words)

	The Lupus Hunter
		Based on the nearly identical structure of the two protein sequences, James suggested that she and Harley investigate a possible link between the virus and lupus.
		He and James decided that the best way to explore the link between Epstein-Barr and lupus was to immunize lab animals with key portions of the virus and see how their immune systems responded.
		But when they examined lupus patients from the same age group, they saw that virtually every one of them tested positive for Epstein-Barr exposure.
	www.omrf.org /OMRF/Information/Findings/2005Fall/LupusHunter4.asp (545 words)

	Virius Lupus - Wikipedia, the free encyclopedia (Site not responding. Last check: 2007-11-06)
		He served as a legatus of one of the German provinces and supported Septimus Severus during the civil war that followed the murder of Pertinax.
		Fearful that they would ally with the Caledonian Confederacy and unable to secure troop reinforcements from Severus, Lupus had no choice but to pay the rebels in return for their withdrawal and the return of a few prisoners.
		His governorship was assisted by the arrival of Sextus Varius Marcellus as provincial procurator and in who can be seen the germ of the later division of Britain into two provinces.
	en.wikipedia.org /wiki/Virius_Lupus (303 words)

	Living with Lupus - lupus erythematosus Nation's Business - Find Articles
		Rheumatologists ran tests but were unable to arrive at a diagnosis other than a very general one of "connective-tissue disease." She was put on anti-inflammatory medication, and her affected arm and leg were encased in casts that she wore for the next 12 years.
		In lupus, the body mistakenly attacks its own cells and tissues as it would a foreign substance, such as a virus.
		Lupus can injure or inflame just about any part of the body--skin, joints, kidneys, lungs, blood, or central nervous system.
	findarticles.com /p/articles/mi_m1154/is_n3_v81/ai_13533163 (660 words)

	HIV & AIDS - HIV - can you be more specific? Open Questions Concerning the Specificity of anti-HIV Antibodies: Do they ...
		Furthermore, we have shown that autoimmune reactions have to be considered as pathological effects of a continuous inflammatory macrophage activity, whereby the increased performance of the immune system for the elimination of exogenous "non-self" structures is directed against endogenous structures.
		In this connection, in systemic autoimmune diseases such as lupus erythematosus the principal factor involved is the continuous hyperactivity of the B-cell functions.
		Lupus erythematosus disseminatus is the prototype of a systemic autoimmune disease with widespread involvement of the different organ systems.
	www.virusmyth.net /aids/data/ahspecific.htm (2255 words)

	Epstein-Barr virus may increase risk of lupus (Site not responding. Last check: 2007-11-06)
		Lupus is a chronic, potentially debilitating autoimmune disease that more often affects women and is also more common in African Americans.
		To determine if there is an association between Epstein-Barr virus and lupus, researchers in North and South Carolina compared the prevalence of EBV antibodies in blood samples from lupus patients with those from healthy controls.
		Among both lupus patients and controls, African Americans had a higher prevalence of EBV-IgG antibodies - the telltale sign of having a history of EBV infection - than white subjects.
	www.news-medical.net /?id=9066 (749 words)

	Need advice please!!
		Have always had many symptoms of lupus but blood test were always neg, so rheumie could only come up w/ FMS.
		I just feel the symptoms are so indicitive of Lupus, but she said my joints werent swollen due to Predisone my neuro had me on 2 weeks age.
		I was not diagnosed with much of anything and I feel that it could be Lupus as my ANA was Positive and I am Anemic and I have joint pain and so on and so on.
	www.suite101.com /discussion.cfm/lupus/100619 (1139 words)

	[No title]
		The Lupus Foundation of America (LFA) was established in 1977 to educate and support those affected by lupus and find the cure.
		Chapters provide support to people with lupus, their families, and friends through support group meetings, hospital visits, and telephone help lines.
		Previous studies have shown that the dysfunctioning T cells, which normally regulate the immune response, coupled with overactive B cells, which target both foreign and healthy cells, are responsible for the destructive autoimmune process that takes place in lupus.
	www.lycos.com /info/lupus--lupus-research.html?page=3 (552 words)

	Epstein-Barr virus and lupus
		Systemic lupus erythematosus, or lupus for short, is the prototype of an autoimmune disease, in which defects in the body’s defense system result in damage ranging from skin rashes to life-threatening kidney and heart disease.
		As part of a Lupus Center of Excellence recently established at the Magee Women's Hospital of the University of Pittsburgh Medical Center, the Pittsburgh team is preparing to launch a multi-center validation study that will hopefully lead to incorporation of their test into routine clinical practice (see box).
		Building on their earlier discoveries of genes that suppress lupus development, the current research suggests that lupus results from an imbalance between genes that increase and genes that suppress the immune system's responsiveness.
	www.arthritis.org /research/ResearchUpdate/05Jan_Feb/Printable.htm (4213 words)

	News - Lupus And The Role Of Epstein-Barr Virus
		Among both lupus patients and controls, African Americans had a higher prevalence of EBV-IgG antibodies -- the telltale sign of having a history of EBV infection -- than white subjects.
		EBV-IgA was found in 66% of African-American patients, and calculated at increasing the odds for lupus by 5 to 6 fold.
		Providing solid new serum-based evidence on the link between lupus and Epstein-Barr virus, this study also calls attention to the need for continued research into the role of race, age, and genetic variation in autoimmune diseases.
	www.docguide.com /news/content.nsf/news/8525697700573E1885256FDC004AFB2F (847 words)

	Defective Control of Latent Epstein-Barr Virus Infection in Systemic Lupus Erythematosus -- Kang et al. 172 (2): 1287 ...
		A and B, Heparinized whole blood from a lupus patient seropositive for EBV and CMV was cultured with various stimuli (staphylococcal enterotoxin B (SEB); control Ag; 30 µl/ml EBV or 50 µl/ml CMV with anti-CD28 and anti-CD49d) for 6 h.
		T cells from lupus-prone mice are hyperresponsive to t cell receptor engagement with low and high affinity peptide antigens: a model to explain spontaneous T cell activation in lupus.
		Impaired nonrestricted cytolytic activity in systemic lupus erythematosus: involvement of a pathway independent of Fas, tumor necrosis factor, and extracellular ATP that is associated with little detectable perforin.
	www.jimmunol.org /cgi/content/full/172/2/1287 (5746 words)

	News - Lupus And The Role Of Epstein-Barr Virus
		Maintaining EBV infection in a latent or quiet state primarily depends on the power of, which play a major role in keeping the immune system functioning properly.
		Among both lupus patients and controls, African Americans had a higher prevalence of EBV-IgG antibodies -- the telltale sign of having a history of EBV infection -- than white subjects.
		EBV-IgA was found in 66% of African-American patients, and calculated at increasing the odds for lupus by 5 to 6 fold.
	docguide.com /news/content.nsf/news/8525697700573E1885256FDC004AFB2F (903 words)

	CRISP - Computer Retrieval of Information on Scientific Projects, Abstract Display (Site not responding. Last check: 2007-11-06)
		Abstract: The genetic basis of systemic lupus erythematosis has been pursued using the last five years of funding from this grant (AR24717-07 to -11) to help perform and evaluate a genome scan in lupus.
		Data show association, are consistent with Epstein-Barr virus infection preceding lupus onset, and advance a plausible mechanism for lupus autoimmunity in some patients.
		Establish linkage using: A. Lupus (by revised ACR criteria), B. An environmental factor and intermediate phenotypes: i.
	crisp.cit.nih.gov /crisp/CRISP_LIB.getdoc?textkey=6700221&p_grant_num=5R01AI024717-16&p_query=(lupus)&ticket=17604582&p_audit_session_id=81899331&p_audit_score=100&p_audit_numfound=7&p_keywords=lupus (248 words)

	Epstein-Barr virus and lupus
		EBV infection is more common in people with systemic lupus erythematosus (SLE or lupus) but it is not clear whether this is a cause or effect of a faulty immune system in these individuals.
		The researchers found that the patients with lupus had a 40-fold increase in signs of EBV infection compared to the healthy subjects.
		The team concluded that people with lupus have a defect in their ability to control latent EBV infection that probably results from altered T cell responses to the virus.
	www.arthritis.org /research/ResearchUpdate/04Jan_Feb/EB.asp (458 words)

	Epstein-barr Virus Linked To Lupus
		According to their article in the December 15th Journal of Clinical Investigation, the researchers documented seroconversion against Epstein-Barr virus in 99% of the patients with lupus, compared with seroconversion in 70% of 153 lupus-free controls.
		In addition, they report that of 32 lupus patients tested, all had Epstein-Barr viral DNA in peripheral blood lymphocytes, compared with 23 of 32 controls.
		is to bring to our attention that (Epstein-Barr virus) may yet be the most dominant environmental factor contributing to (systemic lupus erythematosus)." He continues, "It may act together with genetically souped-up B cells to complete a pathogenetic pathway, or it may require interactions with yet other viruses.
	www.personalmd.com /news/a1997121605.shtml (295 words)

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