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| | Rollin, Mol Vis 2004; 10:450-457. |
 | | Since plasma and vitreous ANP concentrations were found to be unrelated, we suggest intraocular ANP synthesis and/or an increase in the release of ANP into the vitreous, as opposed to diffusion from the blood, as the main factors contributing to the high vitreous ANP levels observed in diabetic patients. |
 | | Undiluted vitreous humor samples were collected at the time of vitreoretinal surgery by using a syringe attached to an automated vitrector before starting the intravitreal infusion of balanced salt solution. |
 | | Vitreous ANP levels were highest in diabetic patients with active PDR (median 60.5 pg/ml, range 57.60-68.5 pg/ml; n=19), followed by diabetic patients with quiescent PDR (median 43.20 pg/ml, range 41.50-45.00 pg/ml; n=3) and those with diabetes without PDR (median 23.1 pg/ml, range 22.10-25.05 pg/ml; n=28) and controls (median, 15.6 pg/ml, range 14.75-16.8 pg/ml; n=29). |
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