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Topic: Whipple disease


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In the News (Sun 8 Nov 09)

  
  Whipple's Disease Information on Healthline
Whipple's disease is a rare infectious disorder that can affect many areas of the body, including the gastrointestinal and central nervous systems.
Whipple's disease, also known as intestinal lipodystrophy, was first reported in 1907 by George Hoyt Whipple (1878–1976).
Whipple's disease has traditionally been regarded as a malabsorption disease of the small intestine, but in most cases the first symptoms are arthritic joints, which can precede the malabsorption symptoms of Whipple's disease by many years.
www.healthline.com /galecontent/whipples-disease   (838 words)

  
 CIGNA - Whipple Disease
Other symptoms of Whipple disease may include: abnormally enlarged lymph nodes that are firm but usually not tender, an abnormally enlarged spleen (splenomegaly), increased color (pigmentation) of the skin, a decrease in blood pressure (hypotension), and abnormally high fevers that come and go.
Ulcerative colitis is an acute inflammatory bowel disease characterized by diarrhea and blood in the stools because of multiple, irregular ulcerations of the bowel.
Immunosuppressive therapy in Whipple’s disease patients is the association with the appearance of gastrointestinal manifestations.
www.cigna.com /healthinfo/nord90.html   (2142 words)

  
  Whipple?s Disease - Health Encyclopedia
Whipple's disease is a rare condition in which infection makes the intestine unable to properly absorb nutrients.
Whipple's disease is most likely caused by infection with Tropheryma whippelii.
Whipple's disease is extremely rare, and risk factors are unknown.
www.wnbc.com /encyclopedia/6859618/detail.html   (504 words)

  
  Whipple's disease - Wikipedia, the free encyclopedia
Whipple's disease is a rare disease caused by the bacteria Tropheryma whipplei and affects the bowel.
Whipple's disease causes weight loss, incomplete breakdown of carbohydrates or fats, and malfunctions of the immune system.
Diseases of the liver - pancreas - gallbladder - biliary tree
en.wikipedia.org /wiki/Whipple's_disease   (191 words)

  
 Whipple: Whipple's Disease and the Whipple Procedure
Whipple's disease is a very rare, infectious disease that causes malabsorption, an inadequate absorption of nutrients.
Whipple's disease is caused by a bacterial infection of the small intestine; however, if given enough time and left untreated, it can spread to other parts of the body.
In the Whipple procedure, the gallbladder, the common bile duct, part of the duodenum (small intestine) and the head of the pancreas are removed.
www.gitract.info /intestinal-disorders/whipple.php   (569 words)

  
 Whipple's Disease Overview
Whipple’s disease is a rare bacterial infection of the small intestine that causes malabsorption of nutrients.
Whipple’s disease is caused by the bacteria Tropheryma whippelli.
Enlargement of the lymph nodes, liver and spleen, fever, abdominal tenderness, fluid in the belly and chest, as well as swollen feet are signs of Whipple’s disease that has spread to other organs in the body.
www.healthinplainenglish.com /health/digestive/whipples_disease   (313 words)

  
 UAB Health System   (Site not responding. Last check: )
Whipple's disease is a rare malabsorption disorder, which means it interferes with the body's ability to absorb certain nutrients from the digestive track.
Whipple's disease is caused by the bacterium Tropheryma whippleii.
Because Whipple's disease is primarily considered a gastrointestinal disorder, gastroenterologists, specialists in the treatment of digestive diseases are the type physician that generally treat this disorder.
www.health.uab.edu /default.aspx?pid=61589   (514 words)

  
 MERSI Ocular Immunology and Uveitis Foundation| Medical Professionals | Articles | Case Reports
Whipple’s disease is rare, multivisceral, and chronic, whose clinical presentation is typically dominated by a symptom triad of diarrhea, weight loss and malabsorption.
Deaths from Whipple's disease are usually a result of lack of antibiotic treatment, central nervous system or cardiac complications, delayed initiation of treatment (terminal disease), failure to diagnose the disease, and irreversible relapse.
Cultivation of Whipple bacillus: the irony and the ecstasy.
www.uveitis.org /medical/articles/case/whip.html   (2844 words)

  
 Bulletin on the Rheumatic Diseases, Volume 51, Number 2 - Whipple's Disease   (Site not responding. Last check: )
Whipple’s disease is a rare multisystemic illness caused by infection with the bacillus Tropheryma whippelii.
The diagnosis of Whipple’s disease is established by duodenal or lymph node biopsy, which demonstrates infiltration of the lamina propia with PAS-positive macrophages that contain Gram-positive bacilli.
O’Duffy et al reported 2 patients presenting with polyarthritis and negative bowel mucosal biopsies for Whipple’s disease in whom the synovial fluid of 1 and the synovial tissue of the other were positive for Tropheryma whippelii when examined by polymerase chain reaction (PCR) and DNA sequencing (27).
www.arthritis.org /research/bulletin/vol51no2/51_2_whipple.asp   (412 words)

  
 Whipple's Disease Symptoms
Whipple's disease: a rare malabsorption syndrome that is caused by an actinomycetous fungus,Tropheryma whippelli, in the mucous membrane of the intestine
Whipple's disease also called intestinal lipodystrophy is a rare infectious disease that typically infects the bowel.
Whipple's disease is caused by bacteria named Tropheryma whippelii.
www.symptoms-4u.com /whipples-disease.htm   (255 words)

  
 Whipple's Disease
Whipple's disease mainly affects men in the age range of 30 to 60.
Whipple's disease is caused by the organism Tropheryma whippelii.
Whipple's disease is diagnosed through a tissue sample (biopsy) of the small intestine, or of an enlarged lymph node.
www.hmc.psu.edu /healthinfo/uz/whipple.htm   (347 words)

  
 Whipple Disease -- Recommendations and Resources   (Site not responding. Last check: )
Born in Ashland, New Hampshire, Whipple attended Andover Academy, Yale University, and Johns Hopkins University, where he got his M.D. He was the first to describe Whipple's disease (named after him) and gave clues as to its cause (bacteria), in 1907.
Whipple became a Council member, and a member of the Committee of Safety, and was elected to the Continental Congress, serving there through 1779.
Whipple was commissioned a captain in the Continental Navy on 22 December and was given command of 24-gun frigate ''Columbus''.
www.becomingapediatrician.com /health/174/whipple-disease.html   (1049 words)

  
 Whipple's Disease
The disease causes weight loss, irregular breakdown of carbohydrates and fats, resistance to insulin, and malfunctions of the immune system.
The disease causes lesions on the wall of the small intestine and thickening of the tissue.
Whipple's disease is treated with antibiotics to destroy the bacteria that cause the disease.
healthlink.mcw.edu /article/930591431.html   (285 words)

  
 Whipple's Disease
Whipple's disease is a rare disorder characterized by the infiltration of the lamina propria of the small intestine by glycoprotein-laden macrophages filled with bacilliform bodies.
The cardiac involvement of Whipple's disease includes the endocardium, myocardium, pericardium, and even the coronary arteries, it is not surprising that these patients occasionally have congestive heart failure and symptomatic pericarditis.
Although this appearance was once thought to be pathognomonic of Whipple's disease, a very similar appearance is seen in some patients with AIDS enteropathy who have intestinal infection with Mycobacterium avium complex disease.
enotes.tripod.com /whipple.htm   (943 words)

  
 Whipple Disease
Whipple disease is a chronic, relapsing, and multisystem disease.
Whipple's disease: Immunospecific and quantitative immunohistochemical study of intestinal biopsy specimens.
Whipple's disease may be diagnosed by periodic acid-Schiff (PAS) staining, electron microscopy, or polymerase chain reaction of intestinal biopsy specimens.
www.thedoctorsdoctor.com /diseases/whipple_disease.htm   (1662 words)

  
 Whipple's Disease
Whipple disease is a rare chronic, relapsing, and multisystem disease caused by bacterial infection.
Decision analysis: an aid to the diagnosis of Whipple's disease.
Whipple's disease confined to the central nervous system: case report and review of the literature.
www.histopathology-india.net /whipple.htm   (355 words)

  
 Whipple's Disease   (Site not responding. Last check: )
Despite being a bacterial infection, the disease does not appear to be contagious.
Individuals with Whipple's disease may have abnormalities of the eye, such as ocular inflammation, vitreous opacities, and supranuclear ophthalmopegia.
Most individuals with Whipple's disease are anemic (have a low red blood cell count).
www.lakeside.ca /Patient_Info/whipples_disease.htm   (479 words)

  
 eMedicine - Whipple Disease : Article by Ingram Roberts, MD
The disease appears to be associated with the human leukocyte antigen B27 (HLA-B27) haplotype.
This suggests that Whipple disease is a manifestation of an abnormal host response to a microorganism that may occur frequently in humans (perhaps in a similar manner to that observed with Helicobacter pylori).
Patients with clinical Whipple disease should be monitored with a PCR test because it is the most sensitive and specific (in contrast to histology) method to determine if they are responding to antibiotic therapy.
www.emedicine.com /med/topic2409.htm   (2322 words)

  
 eMedicine - Whipple Disease : Article Excerpt by: Ingram Roberts, MD
Pathophysiology: The clinical manifestations of the disease are believed to be caused by infiltration of the various body tissues by T whippelii.
The organisms have been detected in the heart valves of patients with cardiac Whipple disease and in the CNS of patients with neurologic disease.
The disease is almost universally fatal after 1 year in patients who do not receive the correct diagnosis and therapy.
www.emedicine.com /med/byname/whipple-disease.htm   (448 words)

  
 Liver: Transplant Surgery Program and Center for Liver Disease
The diseased liver is replaced with a segment of liver from a healthy human donor (usually a relative or close friend).
The diseased liver is replaced with a healthy liver from a "brain dead" human donor.
Pancreatic Surgery: Pancreaticoduodenectomy (Whipple procedure), pylorus preserving Whipple procedure, pancreatic head resection (Beger's operation), lateral pancreaticojejunostomy (Puestow procedure), internal pancreatic pseudocyst drainage, pancreatic debridement and drainage for pancreatic necrosis, autotransplantation of pancreatic islets.
www.livertransplant.org   (391 words)

  
 MedicalGeo.com - Diseases U - Z
A disease is any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person.
Sometimes the term is used broadly to include injuries, disabilities, syndromes, symptoms, deviant behaviors, and atypical variations of structure and function, while in other contexts these may be considered distinguishable categories.
The subject of systematic classification of diseases is referred to as nosology.
www.medicalgeo.com /Med-Diseases-U---Z   (83 words)

  
 Experts' Biographies
Beverly Whipple, a certified sexuality educator, sexuality counselor and sex researcher, is the co author of the international best seller, The G Spot and Other Discoveries About Human Sexuality, which has been translated into 19 languages and was re-published as a classic 23 years later in 2005.
Whipple is a member of a number of honor societies and received the Alumni Achievement Award from Wagner College in 1983.
Whipple was the President of AASECT (1998-2000), the Vice President of the World Association for Sexology (2001-2005), on the Board of the International Society for the Study of Women's Sexual Health (2002-2004) and the President of SSSS (2002-2003).
www.healthywomen.org /columns/healthysexualityasktheexperts/expertsbiographies   (0 words)

  
 EID Vol 2 No 3: Molecular Approaches to the Identification
of Unculturable Infectious Agents
Detecting exogenous DNA in diseased tissue by this technique, however, does not exclude the possibility that a commensal agent may be identified that is not the cause of the disease being examined.
Whipple's disease is a systemic illness, first described in 1907, characterized by arthralgias, diarrhea, abdominal pain, and weight loss (73).
Rod-shaped bacilli were identified histologically in Whipple's disease lesions in the early 1960s (74), but the suspected bacteria were not culturable by standard techniques (73).
www.cdc.gov /ncidod/EID/vol2no3/gao.htm   (5455 words)

  
 Frequently Asked Questions
A notable example is the Whipples of Terrebonne Parish, Louisiana--descendants of George Whipple of Baden-Baden, on the western foothills of the Black Forest in the present-day German state of Baden-Württemberg.
Margaret (Whipple) Rathbone--aunt of the brothers Matthew and John Whipple of Ipswich, Massachusetts--was buried in Bocking on 19 Jan 1627/8.
Whipple's disease is a multisystem disorder caused by chronic infection with a bacterium, Tropheryma whippelii.
www.whipple.org /docs/faqs.html   (3963 words)

  
 MayoClinic.com Health Library - Whipple's disease
Whipple's disease is rare and many doctors may be unfamiliar with the disorder, so it's often diagnosed in its late stages.
To diagnose Whipple's disease, your doctor may begin with a complete physical exam, looking for signs and symptoms that suggest the presence of the condition — for example, abdominal tenderness and skin darkening, particularly on sun-exposed parts of your body.
Whipple's disease is a progressive and potentially fatal disease.
www.riverside-online.com /health_reference/Infectious-Disease/DS00757.cfm   (1326 words)

  
 Whipple's Disease
Whipple's Disease is a rare infectious disease that causes an abnormality in the metabolism and/or usage of fats (lipodystrophy) in the small intestine (localized) characterized by impairment of the ability to properly absorb nutrients (malabsorption), anemia, and joint pain.
Whipple's Disease may be diagnosed by ultrasound tests and CT scan that may reveal abnormally enlarged lymph nodes (lymphadenopathy) and/or a thickening of the lining of the small intestine.
Whipple's Disease is a rare disorder that affects more males than females in a ratio of 8 males to 1 female.
hw.healthdialog.com /kbase/nord/nord90.htm   (1947 words)

  
 Whipple's disease (www.whonamedit.com)
In the past, the disease was predominant in males, with onset usually between the ages of 30 and 50.
Whipple in 1907 described a medical missionary with a condition "characterized by a gradual loss of weight and strength, stools consisting chiefly of neutral fat and fatty acids, indefinite abdominal signs, and a peculiar multiple arthritis".
The disease picture reported by Whipple had been described as early as in 1895 by Sir William Henry Allchin (1846-1922) and Richard Grainger Hebb (1848-1918).
www.whonamedit.com /synd.cfm/3892.html   (287 words)

  
 Whipple's Disease: Malabsorption: Merck Manual Home Edition
Whipple's disease (intestinal lipodystrophy) is the result of a rare bacterial infection that damages the lining of the small intestine and may involve other organs of the body.
It is caused by an infection with the organism Tropheryma whippelii.
A doctor can make the diagnosis of Whipple's disease when a biopsy (a microscopic examination of tissue) of the small intestine or of an enlarged lymph node demonstrates the bacteria.
www.merck.com /mmhe/sec09/ch125/ch125e.html   (243 words)

  
 Whipple's Disease and "Tropheryma whippelii" -- Dutly and Altwegg 14 (3): 561 -- Clinical Microbiology Reviews
Whipple's disease is a rare bacterial infection that may involve any organ system in the body.
Whipple's disease were also described (7, 91, 111).
Whipple's disease (56, 181) is due to the presence of pathogenic
cmr.asm.org /cgi/content/full/14/3/561   (8938 words)

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