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Topic: William S Knowles


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In the News (Sat 26 Dec 09)

  
  Company News On Call
Dr. Knowles was a long-time employee of Monsanto and is receiving the Nobel Prize for scientific breakthroughs achieved while working for Monsanto in 1968.
Dr. Knowles was a recipient of the highest honors Monsanto bestows on its scientists for their contributions to science and technology.
Knowles, Vineyard and Sabacky are also Monsanto Fellows, a program that recognizes and rewards scientists for breakthroughs and encourages continued contributions in their areas of expertise.
www.prnewswire.com /cgi-bin/stories.pl?ACCT=105&STORY=/www/story/10-10-2001/0001589373   (410 words)

  
 10 Oct History: This Date
Knowles exchanged the non-chiral phosphine triphenylphosphine in A to the chiral phosphine B and obtained a catalyst for asymmetric hydrogenation.
Knowles' hypothesis was that it might be possible to produce a catalyst for asymmetric hydrogenation if the triphenylphosphine groups in Osborn and Wilkinson's metal complex (A) was replaced by one of the enantiomers of a chiral phosphine.
Knowles' aim was to develop an industrial synthesis of the amino acid L-DOPA, which had proved useful in the treatment of Parkinson's disease — a discovery for which A. Carlsson was awarded last year's Nobel Prize in Physiology or Medicine.
www.safran-arts.com /42day/history/nobel/nob1010.html   (8143 words)

  
 C&EN: SCIENCE & TECHNOLOGY - WILLIAM WHO?
"William Who?" Some chemists might be forgiven for asking that question several weeks ago when the Royal Swedish Academy of Sciences awarded the 2001 Nobel Prize in Chemistry to Monsanto retiree William S. Knowles; chemistry professor Ryoji Noyori of Nagoya University, in Japan; and chemistry professor K.
Knowles has been less well known than the other two new chemistry laureates, Jacobsen explains, "partly because he worked in industry and partly because the work that he did is now 30 years old.
At Monsanto, Knowles had specialized in exploratory process development on organic chemicals and intermediates, including fine chemicals and plasticizers, but after the postdoc with Woodward, he began a program on the total synthesis of steroids.
pubs.acs.org /cen/topstory/7945/7945sci1.html   (1744 words)

  
 Andover Bulletin - Fall 2002 - William S. Knowles
William S. Knowles ’35, above left, was awarded the Nobel Prize in Chemistry by the Royal Swedish Academy of Sciences in October 2001.
Three scientists shared the $1 million prize: Knowles and Ryoji Noyori of Nagoya University in Japan for their work on chirally catalyzed hydrogenation reactions and K. Barry Sharpless of the Scripps Research Institute in California for his work on chirally catalysed oxidation reactions.
Specifically, Knowles’ work in using transition metals to make chiral catalysts for an important type of reaction called hydrogenation pioneered an industrial process for the production of the drug L-DOPA, which is used in the treatment of Parkinson’s disease.
www.andover.edu /publications/alumni_profiles/knowles_w_fal_02.htm   (225 words)

  
 KATU 2 - Portland, Oregon   (Site not responding. Last check: 2007-10-18)
Knowles is being held in a Multnomah County detention center on an accusation of traveling in interstate commerce with the purpose of engaging in illicit sexual conduct with a minor.
Knowles' court-appointed attorney, Nancy Bergeson, an assistant federal defender, told the U.S. Magistrate Dennis Hubel that Knowles' financial situation is "pretty dismal" and that he cooperated with authorities.
Knowles denied arranging to meet the girl for sex and said he planned to meet a woman to have sex, according to court records.
www.katu.com /news/story.asp?ID=69319   (545 words)

  
 Association of Flight Attendants, AFL-CIO v. Horizon Air Industries, Inc.
This Court reversed the district court' s granting of summary judgment, finding that although Fennessy' s grievance had been submitted to the Board, his complaint stated an independent statutory claim under Section 152, Fourth, which could be brought directly to district court.
Moreover, the facts of this case support the district court' s conclusion that the issue presented by AFA is a minor dispute because Horizon' s policy is "arguably justified" under the existing AFA-Horizon CBA.
The district court properly concluded that the dispute concerning AFA' s members' rights to wear AFA union pins fell within the AFA-Horizon CBA and was a matter for arbitration rather than district court litigation.
www.law.com /regionals/ca/opinions/feb/0035129.shtml   (1884 words)

  
 Boston.com / Latest News / Nation
Knowles, who retired from Monsanto in 1986 after 44 years with the company, shares the prize with another American and a Japanese scientist for discoveries now used to make various medicines, including antibiotics, heart drugs and a widely used treatment for Parkinson's disease.
Knowles and Ryoji Noyori, 63, of Nagoya University in Japan shared half of the $943,000 award.
Born in 1917 in Taunton, Mass., and reared in New Bedford, Knowles even as a young child wanted to be a scientist and made it happen, getting a chemistry degree from Harvard in 1939, then a graduate degree in the field from Columbia three years later.
www.boston.com /news/daily/10/knowles.htm   (696 words)

  
 Pharmacia Corporation Congratulates Nobel Prize Winner Williams S. Knowles for Pioneering Chemistry Research
Dr. Knowles received the Nobel Prize for research conducted in 1968 that led to the successful commercial production of levodopa, a medicine for the treatment of Parkinson's disease.
Knowles' research was later applied in the synthesis of antibiotics, anti-inflammatory drugs and heart medicines.
"The advances in synthetic chemistry pioneered by Dr. Knowles more than 30 years ago transformed the lives of patients with Parkinson's disease and led to the successful development of new medicines in other therapeutic areas." Pharmacia Corporation (NYSE: PHA) is a top-tier global pharmaceutical company with a leading agricultural subsidiary.
www.prnewswire.com /cgi-bin/stories.pl?ACCT=104&STORY=/www/story/10-12-2001/0001590732&EDATE=   (279 words)

  
 SunSITE India : 2001 Nobel Chemistry prize   (Site not responding. Last check: 2007-10-18)
William S. Knowles discovered that it was possible to use transition metals to make chiral catalysts for an important type of reaction called hydrogenation, thereby obtaining the desired mirror image form as the final product.
Today the results of their basic research are being used in a number of industrial syntheses of pharmaceutical products such as antibiotics, anti-inflammatory drugs and heart medicines.
William S. Knowles, 84 years, born 1917 (US citizen).
sunsite.iisc.ernet.in /nobel2001/che2001_rel.html   (483 words)

  
 KNOWLES FAMILY 1821 in UK to 2005 In CLEVELAND, Oh. USA   (Site not responding. Last check: 2007-10-18)
Little Leonora s father would often make her go with him on saturday (his day off) as he went drinking from pub to pub.
Joseph Knowles preached on occasion in thier local church,an that William was a good student.Principles and values / Though grandparents had varied backgrounds,they both reached maturity with a strong sence of honesty, of duty,of discipline and high moral principles.
Frank,Lillian,and F. William Knowles made visit to Birmingham 1n 1980 an found home on Newcome road where Tom was born in 1905.
members.aol.com /__121b_fLnmvGwdnTWhfuzzzMpfVJUDnnxGGygNEEKCjcFQyewCeqcbIRj2dg==   (1983 words)

  
 Nobel in Chemistry Awarded   (Site not responding. Last check: 2007-10-18)
The Nobel Prize in Chemistry for 2001 was awarded Wednesday, October 10, to William S. Knowles (U.S.), Ryoji Noyori (Japan), and K. Barry Sharpless (U.S.) for their development of catalytic asymmetric synthesis.
Nobel laureates Knowles and Noyori shared half of the prize for "their development of chirally catalysed hydrogenation reactions", and laureate Sharpless was awarded the other half for "his work on chirally catalyzed oxidation reactions", according to the Royal Swedish Academy of Sciences.
Knowles had added a hydrogen molecule to a double bond between two carbon molecules.
www.acs.org /portal/a/c/s/1/feature_acs.html?id=a3132d2ecc8611d5ea024fd8fe800100   (386 words)

  
 Pollock   (Site not responding. Last check: 2007-10-18)
Knowles to England, and while he resided at Bristol, he executed a deed, dated Mar. 15 1654/5, conveying his estate in Watertown, for the sum of 200 pounds, to William Bond, in the possession of whose descendants it remained more than 170 years.
Richard Knowles was not one of the, first company to go out to the settlement which was to be the future home of his family.
In 1669 Richard Knowles and William Walker were elected surveyors of highways, and in the next year Richard Knowles and Samuel Freeman were elected to the same office.The records of the Eastham town meetings contain several references to the land of Richard Knowles and his sons John and Samuel.
members.surfbest.net /krob/Pollock.htm   (4272 words)

  
 William Wallace Knowles Genealogy Source Records
William Knowles, Bachelor and Isabella Catherine Black, spinster, were married with license this Twenty fifth day of January Eighteen Hundred and Seventy seven by me.
William Knowles and Isabella Black were married on January 25, 1877 in Montreal.
William Knowles, formerly of Cavan Ireland to Isabella Catherine, oldest daughter of Thomas Black Esq., of this city.
homepage.mac.com /ourhistory/Knowles/Records/GSR_Knowles_WilliamWallace.html   (1772 words)

  
 Columbia News ::: Nobel Prize Winner in Chemistry Earned Doctorate at Columbia
William S. Knowles, who shared the 2001 Nobel Prize in chemistry for pioneering research that led to the development of hundreds of drugs to treat diseases ranging from AIDS to Parkinson's disease, earned his Ph.D. at Columbia in 1942.
Knowles' breakthrough dates to 1968 when he was working for Monsanto.
He discovered that it was possible to use transition metals to make chiral catalysts for an important type of reaction called hydrogenation.
www.columbia.edu /cu/news/01/10/williamSKnowles.html   (368 words)

  
 Search Results for thalidomide - Encyclopædia Britannica   (Site not responding. Last check: 2007-10-18)
Knowles, William S. American chemist who, with Noyori Ryoji and K. Barry Sharpless, won the Nobel Prize for Chemistry in 2001 for developing the first chiral catalysts.
Japanese chemist who, with K. Barry Sharpless and William S. Knowles, won the Nobel Prize for Chemistry in 2001 for developing the first chiral catalysts.
American scientist who, with William S. Knowles and Noyori Ryoji, won the Nobel Prize for Chemistry in 2001 for developing the first chiral catalysts.
www.britannica.com /search?query=thalidomide&submit=Find&source=MWTAB   (396 words)

  
 Obituaries: 9/8/01
Born in Cumberland, Md., son of the late William and Alice (Shaw) Knowles, he lived in the New Bedford/Dartmouth area most of his life, spending some time in Holyoke during the 1940's and 50's.
Knowles served in the Navy on the USS Franklin Delano Roosevelt during the Korean War.
She was the sister of the late John Moss, William Moss, Victor Moss, Rene Moss, Charles Moss, Peter Moss, Joseph Moss, Mary Shaw and Lillian Moss.
www.s-t.com /daily/09-01/09-08-01/zzzddobi.htm   (3019 words)

  
 77Knowles   (Site not responding. Last check: 2007-10-18)
Later that night, when Knowles went to work, he parked his car on A Avenue leaving the door open so that he could hear his radio as he patrolled south on State Street.
He told Knowles that he had opened that back door and that his partner was waiting for him with an axe.
Knowles served as Police Chief for a number of years, later working for the Division of Motor Vehicles.
www.europa.com /~heritage/77Knowles.html   (748 words)

  
 Washington University - News & Information
he scholarship's namesake is the 2001 recipient of the Nobel Prize in Chemistry, which Knowles shared with Ryoji Noyori of Nagoya University in Nagoya, Japan, and K. Barry Sharpless of the Scripps Research Institute in La Jolla, California.
Knowles discovered that it was possible to use transition metals to make chiral catalysts for an important type of reaction called hydrogenation, thereby obtaining the desired mirror image form as the final product.
Knowles helped open up a brand new field of research in which it is possible to synthesize molecules and material with new properties, leading to the development of pharmaceutical products such as antibiotics, anti-inflammatory drugs and heart medicines.
news-info.wustl.edu /News/2002/monsanto.html   (444 words)

  
 Catalysts all the way
JAMES A. Winners of the Nobel Prize for Chemistry William S. Knowles, Ryoji Noyori and K. Barry Sharpless for key research that has been used to create numerous products, including antibiotics and heart drugs.
Knowles achieved the breakthrough in 1968 when he discovered that a transition metal based chiral catalyst could transfer chirality or handedness to a non-chiral substrate and get a chiral product.
Knowles' experiments, based on two earlier discoveries, was to develop an industrial synthesis of the amino acid L-DOPA which was known to be useful in treating Parkinson's disease.
www.flonnet.com /fl1822/18220590.htm   (1115 words)

  
 Knowles Genealogy Photoblog
Gravestone of John W. Knowles (1749-1838) in White County, Tennessee.
Gravestone of William W. Knowles (1815-1860) in White County, Tennessee.
Gravestone of William W. Knowles (1815-1860) in Wh...
knowlesgenealogy-photoblog.blogspot.com   (141 words)

  
 Life stories: Patrick H. Knowles   (Site not responding. Last check: 2007-10-18)
Knowles was born Oct. 24, 1935, in New York City to William J. Knowles and Mary O’Neil Knowles.
He married Barbara J. Torrance on April 23, 1960, in Brooklyn, N.Y. He graduated from Mount St. Mary’s College in Emmitsburg, Md., in 1959 and earned a master’s degree in public health from MU in 1974.
Knowles is survived by his wife; two sons, David A. Knowles of Atlanta and Patrick H. Knowles of Norwich, Conn.; a daughter, Susan B. Knowles of St. Louis; a brother, William J. Knowles of Charleston, S.C.; a sister, Mary C. Rogers of Charleston; and four grandchildren.
www.digmo.com /obits/obit.php?ID=384   (113 words)

  
 History of Pasco County, Florida   (Site not responding. Last check: 2007-10-18)
In 1978, William Knowles, then 83, was living in the same house where he took his bride in 1916, although the house had been moved from Main Street to Hudson Avenue.
In 1978, daughter Essie Knowles Hamilton, then Hudson's longest residing citizen, recalled that her parents met and married in the Hudson area in 1887, when Knowles first came to Hudson from the Bahamas.
Benjamin's son Robert S. Meyer (two years old in the 1870 census) was a keeper of the Anclote lighthouse from October 1889 to February 1933.
fivay.org /pasco2.html   (21414 words)

  
 Encyclopedia: William S. Knowles   (Site not responding. Last check: 2007-10-18)
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William S. Knowles (born June 1, 1917) is a American chemist.
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www.nationmaster.com /encyclopedia/William-S.-Knowles   (169 words)

  
 H.M.S. Hood Association-Battle Cruiser Hood: Photos and Graphics- The Knowles Photo Collection   (Site not responding. Last check: 2007-10-18)
The photos show his father, Able Seaman William Knowles and fellow crewmembers on Hood.
William served in Hood from 7 January 1926 until 27 August 1927 and was a member of her championship rowing teams.
These photos are copyrighted 2001 by Barrie Knowles and may not be downloaded and/or used elsewhere without his express permission.
www.hmshood.org.uk /photos/knowles/knowles1.html   (150 words)

  
 Dr. William Knowles   (Site not responding. Last check: 2007-10-18)
William S. Knowles, Ph.D., 2001 Nobel Laureate in Chemistry,
Dr. Knowles received the Royal Swedish Academy of Sciences’ 2001 Nobel Prize in Chemistry for the development of catalytic asymmetric synthesis, which allowed for the production of L-DOPA by direct chemical synthesis without producing the molecule's mirror image.
The results of their basic research are being used in a number of industrial syntheses of pharmaceutical products such as antibiotics, anti-inflammatory drugs and heart medicines.
www.jracademy.com /FellowsPictures/fellowspages/knowles.html   (107 words)

  
 Science & Technology at Scientific American.com: Nobel Prize in Chemistry Awarded for Discovery of Catalytic ...   (Site not responding. Last check: 2007-10-18)
This year's recipients of the Nobel Prize in Chemistry—William S. Knowles, Ryoji Noyori and K. Barry Sharpless—are honored for their work developing chiral molecules as catalysts.
For their efforts, Knowles and Noyori share half the prize, and Sharpless receives the other half.
William S. Knowles(below at left), now retired, discovered the first example of catalytic asymmetric synthesis in 1968 while he was a chemist for the Monsanto Corporation.
www.sciam.com /article.cfm?articleid=00063537-E5B2-1C63-B882809EC588ED9F   (431 words)

  
 Cupola's Arts and Crafts Architecture - Rose House
Historical sources credit William F. Knowles with the design of this shingled house on a very constrained hillside lot, built for an attorney in 1900.
While not exactly the most handsome composition, it falls nicely into that fun category of buildings that combine the vernacular with the avant garde.
Some years later, Knowles designed the neighboring Hammond House down the hill.
www.cupola.com /html/bldgstru/artscrft/slide/3236k01e.htm   (184 words)

  
 County Obituaries K-O | The San Diego Union-Tribune
William N. Knowles, 75, of La Jolla died Wednesday.
He was born in Asheville and owned Knowles Gallery.
Survivors include his wife, Mary; daughters, Marcia Ellison of San Diego and Laura Spencer of Pahrump, Nev.; sisters, Betty Riggs of Charleston, S.C., and Peggy Simpson of Atlanta; brother, Tommy Wood of Little Rock, Ark.; and five grandchildren.
www.signonsandiego.com /uniontrib/20040419/news_1m19obitsko.html   (344 words)

  
 Bagshot Park, Bagshot and Sussex   (Site not responding. Last check: 2007-10-18)
Charles William KNOWLES was the Head Gardener at Bagshot Park in the first 25 or so years of the last century.
This is the Head Gardener's House at Bagshot Park where Charles William Knowles lived with his wife and son Charles William Knowles Jnr.
Charles William Knowles recounts in his article, the planting of a pinetum at Bagshot Park.
www.hmsweb.co.uk /html/bagshot.html   (168 words)

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