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| | 1-aza-bicyclico(2.2.1)heptanes - Patent 5091397 |
 | | A compound according to claim 1 wherein the 5-membered aromatic ring is selected from 1,2,4-oxadiazol-5-yl, 1,2,4-oxadiazol-3-yl, 1,3,4-oxadiazol-2-yl, 1,3-oxazol-2-yl, 1,3-oxazol-4-yl 1,3-oxazol-5-yl, 1,2-oxazol-3-yl, 1,2-oxazol-5-yl, 1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-2-yl, 1,3-thiazol-2-yl, 1,3-thiazol-5-yl, 1,2-thiazol-5-yl, furan-2-yl, furan-3-yl, 1,2,3-triazol-4-yl and 2H-tetrazol-5-yl. |
 | | A compound according to claim 1, wherein R.sub.1, R.sub.2 and R.sub.3 are independently selected from hydrogen, halogen, N(R.sub.4.sup.1).sub.2, C.sub.2-3 alkenyl, C.sub.2-3 alkynyl, cyclopropyl or C.sub.1-2 alkyl optionally substituted with one, two or three fluorine atoms, in which R.sub.4.sup.1 is hydrogen or methyl. |
 | | A compound according to claim 1, where Z is selected from 3-amino-1,2,4-oxadiazol-5-yl, 3-methyl-1,2,4-oxadiazol-5-yl, 1,3-oxazol-2-yl, 1,3-oxazol-5-yl, 2-methyl-2H-tetrazol-5-yl, 2-furyl, 5-methyl-1,2,4-oxadiazol-3-yl and 1,3-thiazol-2-yl. |
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