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| | BioMed Central | Full text | Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of ... |
 | | RFC message was expressed also in the trophoblastic giant cells, labyrinth, junctional zone, yolk sac and within the neural tube of the developing embryo (Figure 1A and 1C). |
 | | Immunofluorescence showed that RFC protein was present widely throughout the placenta with particularly intense expression in the trophoblastic giant cells, the yolk sac and within the neural tube of the developing embryo (Figure 1B and 1D). |
 | | While RFC expression is most strongly present in specialized cell-types in adult mice, during development RFC mRNA and protein are expressed in the placenta, yolk sac and throughout the embryo, with higher levels of expression being confined to cell populations in the neural tube, forebrain, hindbrain, craniofacial region, eye, limb buds, heart, somites and tail. |
| www.biomedcentral.com /1471-213X/3/6 (2693 words) |
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