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| | COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae (Site not responding. Last check: 2007-10-09) |
 | | The CSN has been implicated both in the phosphorylation of numerous regulatory proteins, such as Jun and p53 (Seeger et al., 1998; Naumann et al., 1999; Bech-Otschir et al., 2001), and in the removal of Nedd8/Rub1 ubiquitin-like modification from the cullin subunit of E3 ubiquitin ligases (Lyapina et al., 2001; Zhou et al., 2001). |
 | | Yang, X., Menon, S., Lykke-Andersen, K., Tsuge, T., Di Xiao, Wang, X., Rodriguez-Suarez, R.J., Zhang, H. and Wei, N. (2002) The COP9 signalosome inhibits p27(kip1) degradation and impedes G1S phase progression via deneddylation of SCF cul1. |
 | | Zhou, C., Seibert, V., Geyer, R., Rhee, E., Lyapina, S., Cope, G., Deshaies, R.J. and Wolf, D.A. (2001) The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p. |
| www.nature.com /cgi-taf/DynaPage.taf?file=/embor/journal/v3/n12/full/embor023.html (3812 words) |
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