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Topic: Zollinger Ellison syndrome


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In the News (Sun 27 Dec 09)

  
  Zollinger-Ellison syndrome - Wikipedia, the free encyclopedia
Zollinger-Ellison syndrome is a disorder where increased levels of the hormone gastrin are produced, causing the stomach to produce excess hydrochloric acid.
Often, the cause is a tumour of the pancreas producing the hormone gastrin.
Zollinger-Ellison syndrome is caused by tumors usually found in the head of the pancreas and the upper small bowel.
en.wikipedia.org /wiki/Zollinger-Ellison_Syndrome   (324 words)

  
 Zollinger-Ellison Syndrome (Gastrinoma) Overview
Zollinger-Ellison syndrome is a rare digestive disorder caused by a tumor of the pancreas called gastrinoma.
Zollinger-Ellison syndrome is caused by a tumor (or tumors) called gastrinoma that affects commonly the pancreas.
Zollinger-Ellison syndrome may also be a part of a larger condition called multiple endocrine neoplasia-I, an inherited form of cancer with tumors not only in the digestive tract, but also the pituitary glands and parathyroid.
healthinplainenglish.com /health/digestive/zollinger_ellison_syndrome   (397 words)

  
 Surgery Helps Zollinger-ellison Syndrome Patients
The researchers recommend that surgery should be offered to all patients with the Zollinger-Ellison syndrome who do not also have a related disorder known as multiple endocrine neoplasia type 1 or metastatic disease.
Hormone-producing tumors called gastrinomas were detected during surgical exploration in 93% of patients, despite the fact that imaging studies were negative in approximately one third of patients.
In contrast, none of the patients with multiple endocrine neoplasia type 1, a syndrome that features tumors in multiple endocrine organs, were disease-free, they add.
www.personalmd.com /news/a1999082507.shtml   (376 words)

  
 Zollinger-Ellison Syndrome
The syndrome was first reported in 1955 by Zollinger and Ellison.
Zollinger-Ellison syndrome occurs in approximately 50% of the patients with multiple endocrine adenomatosis (M.E.A.) Type I. This syndrome includes hyperplasia and/or tumors of the parathyroids, pancreatic islets and pituitary.
The diagnosis of Zollinger-Ellison syndrome is made on the demonstration of high serum gastrin levels.
brighamrad.harvard.edu /Cases/jpnm/hcache/1056/full.html   (1012 words)

  
 Introduction: Zollinger-Ellison syndrome - WrongDiagnosis.com
Zollinger-Ellison syndrome: Zollinger-Ellison syndrome is a rare disorder that causes tumors in the pancreas and duodenum and ulcers in the stomach and duodenum.
Researching symptoms of Zollinger-Ellison syndrome: Further information about the symptoms of Zollinger-Ellison syndrome is available including a list of symptoms of Zollinger-Ellison syndrome, or alternatively return to research other symptoms in the symptom center.
Statistics and Zollinger-Ellison syndrome: Various sources and calculations are available in statistics about Zollinger-Ellison syndrome, prevalence and incidence statistics for Zollinger-Ellison syndrome, and you can also research other medical statistics in our statistics center.
www.wrongdiagnosis.com /z/zollinger_ellison_syndrome/intro.htm   (330 words)

  
 Zollinger-Ellison Syndrome - causes, gastrin, peptic ulcer, malignant tumour, symptoms
Zollinger-Ellison syndrome is the name that doctors use to describe a collection of symptoms arising from the stomach and part of the small bowel called the duodenum (the part of the small intestine leaving the stomach), which occur because the stomach makes too much acid all the time.
Zollinger-Ellison syndrome is a rare disorder in which lumps (tumours) in the pancreas or, less often, in the wall of the duodenum secrete a chemical hormone (signal carried in the blood) substance (called gastrin) that causes the stomach to produce too much acid.
The syndrome is serious and potentially life-threatening because the tumours producing the gastrin may spread.
www.patienthealthinternational.com /article/501579.aspx   (423 words)

  
 Zollinger-Ellison syndrome - OhioHealth   (Site not responding. Last check: 2007-11-06)
The ulcers that occur as part of Zollinger-Ellison syndrome are typically more resistant to treatment than are other ulcers, can recur after initial treatment, are often numerous and may occur in unusual areas of your stomach or intestine.
In Zollinger-Ellison syndrome, tumors form in the pancreas or duodenum — the upper portion of the small intestine.
If you have Zollinger-Ellison syndrome, earlier detection and treatment may be able to halt the spread of any malignant tumors to other organs or lymph nodes.
www.ohiohealth.com /healthreference/reference/00895C9E-1914-4475-86F645783A952DE7.htm   (1274 words)

  
 What is Zollinger-Ellison Syndrome
Zollinger-Ellison Syndrome is a rare condition that causes severe stomach ulcers.
Zollinger-Ellison Syndrome may occur at any age, but it is more likely to appear between the ages of 30 and 60 years old.
In very severe cases of Zollinger-Ellison Syndrome, the entire stomach may have to be surgically removed.
www.mamashealth.com /syndrome/zoll.asp   (224 words)

  
 NEJM -- Cushing's syndrome in patients with the Zollinger-Ellison syndrome
Thus, Cushing's syndrome is more common in patients with the Zollinger-Ellison syndrome than was previously reported, occurring in 8 percent of all cases.
Furthermore, Cushing's syndrome in patients with sporadic Zollinger-Ellison syndrome and in those with multiple endocrine neoplasia type 1 differ in incidence, cause, clinical severity, extent of gastrinoma, the need for therapy, and prognosis.
All patients with the Zollinger-Ellison syndrome and all patients with multiple endocrine neoplasia type 1 should be screened for Cushing's syndrome.
content.nejm.org /cgi/content/short/315/1/1   (405 words)

  
 Strøm-Zollinger-Ellison syndrome (www.whonamedit.com)   (Site not responding. Last check: 2007-11-06)
Gastric hypersecretion-peptic ulceration-pancreatic tumor syndrome, gastric hypersecretion-peptic ulceration syndrome, multiple partial adenomatosis syndrome, multiple partial endocrine adenomatosis syndrome, polyglandular adenomatosis syndrome, ulcerogenic tumor of pancreas syndrome, ulcerogenic tumor syndrome.
This condition comprises a clinical triad of 1) hypesecretion of gastrin, 2) multiple, atypically located, often recurrent peptic ulcers, and 3) a noninsulin producing islet cell tumor of the pancreas.
When associated with familial multiple endocrine adenomatosis, the syndrome is known as the multiple endocrine neoplasia I syndrome.
www.whonamedit.com /synd.cfm/3074.html   (234 words)

  
 Zollinger-Ellison syndrome   (Site not responding. Last check: 2007-11-06)
May also be found rarely in the mesentery, peritoneum, spleen, skin or mediastinum (possibly metastasis with primary not identified).
Prospective study of somatostatin receptor scintigraphy and its effect on operative outcome in patients with Zollinger-Ellison syndrome.
Prospective study of the clinical course, prognostic factors, causes of death, and survival in patients with long-standing Zollinger-Ellison syndrome.
www.5mcc.com /Assets/SUMMARY/TP1012.html   (186 words)

  
 Protonix (Pantoprazole Sodium) Delayed-Release Tablets Approved For Long-Term Treatment of Zollinger-Ellison Syndrome   (Site not responding. Last check: 2007-11-06)
Zollinger-Ellison Syndrome is a rare disease typically affecting people between the ages of 30 and 50.
It is caused by a neuroendocrine tumor called a gastrinoma that is usually located in the pancreas or the duodenum, a portion of the small intestine.
The drug is indicated for the treatment of pathological hypersecretory conditions associated with Zollinger-Ellison Syndrome or other neoplastic conditions.
www.pslgroup.com /dg/2153ae.htm   (1068 words)

  
 eMedicine - Zollinger-Ellison Syndrome : Article by Praveen Roy, MD
Background: Zollinger-Ellison syndrome (ZES) is caused by a non–beta islet cell, gastrin-secreting tumor of the pancreas that stimulates the acid-secreting cells of the stomach to maximal activity, with consequent gastrointestinal mucosal ulceration.
Ellison EC, Sparks J: Zollinger-Ellison syndrome in the era of effective acid suppression: are we unknowingly growing tumors?.
Gibril F, Lindeman RJ, Abou-Saif A: Retained gastric antrum syndrome: a forgotten, treatable cause of refractory peptic ulcer disease.
www.emedicine.com /MED/topic2437.htm   (3086 words)

  
 Zollinger-Ellison Syndrome -- eCureMe.com
Zollinger-Ellison syndrome is a disease process associated with the development of ulcers due to over secretion of gastrin.
This causes an excess of acid to be produced, which results in ulcers.
Once the diagnosis is made, the doctor should check the levels of other hormones that can sometimes be abnormal in patients with Zollinger-Ellison syndrome.
www.ecureme.com /emyhealth/data/Zollinger-Ellison_Syndrome.asp   (497 words)

  
 Healthopedia.com - Zollinger-Ellison Syndrome (Symptomatic Gastrinoma)
The Zollinger-Ellison syndrome (ZES) is a set of symptoms that are caused by cancerous tumors called gastrinomas.
In Zollinger-Ellison syndrome, tumors called gastrinomas produce large amounts of gastrin.
Zollinger-Ellison syndrome is caused by a form of cancer known as a gastrinoma.
www.healthopedia.com /zollinger-ellison-syndrome   (343 words)

  
 Zollinger Ellison Syndrome
It is possible that the main title of the report Zollinger Ellison Syndrome is not the name you expected.
Zollinger-Ellison syndrome (ZES) is characterized by the development of a tumor (gastrinoma) or tumors that secrete excessive levels of gastrin, a hormone that stimulates production of acid by the stomach.
In approximately 25 percent of cases, ZES occurs in association with a genetic syndrome known as multiple endocrine neoplasia type 1 (MEN-1).
my.webmd.com /hw/cancer/nord360.asp   (507 words)

  
 Zollinger-Ellison syndrome
Zollinger-Ellison syndrome is a rare condition that causes tumours to develop in the pancreas.
These tumours are cancerous in half of all cases, and they secrete a hormone called gastrin that provokes the stomach into over-producing gastric acid.
The syndrome most often affects people aged between 30-60, and its cause is not known.
www.irishhealth.com /?level=4&id=498   (215 words)

  
 dreddyclinic.com - Zollinger-Ellison Syndrome
Zollinger-Ellison syndrome is a condition in which one or more tumors form in the pancreas or in the upper part of the small intestine (duodenum).
The ulcers that occur as part of Zollinger-Ellison syndrome are typically more resistant to treatment than other ulcers, may recur after initial treatment, are often numerous and may occur in unusual areas of your stomach or intestine.
It may occur at any age, but it's more likely to occur in people between the ages of 30 and 60.
www.dreddyclinic.com /findinformation/zz/zollingerellisonsyndrome.htm   (332 words)

  
 Zollinger-Ellison Syndrome Discussion
Zollinger-Ellison syndrome (ZES) is a rare disorder that causes tumors in the pancreas and duodenum and ulcers in the stomach and duodenum.
To obtain this information, you may view the results of the automatic search on Zollinger-Ellison Syndrome.
This is a paragraph of text that could go in the sidebar.
aaaaq.com /digestive_diseases/Zollinger-Ellison_syndrome   (613 words)

  
 Clinical Trial: Treatment of Zollinger-Ellison Syndrome
This protocol describes the use of histamine H2-receptor antagonists to control gastric acid hypersecretion in patients with Zollinger-Ellison syndrome.
It details which patients will be considered for treatment with these agents, the pretreatment procedures and the procedures to be followed in establishing the proper intravenous dose of histamine H2-receptor antagonist.
It will also be possible to evaluate the effectiveness of histamine H2-receptor in patients with Zollinger-Ellison syndrome after successful gastrinoma resection who continue to have mild gastric hypersecretion.
clinicaltrials.gov /show/NCT00001241   (478 words)

  
 Zollinger-Ellison Syndrome - StopGettingSick News
Zollinger-Ellison syndrome is a rare disorder that causes tumors in the pancreas and duodenum and ulcers in the stomach and duodenum.
What causes people with Zollinger-Ellison syndrome to develop tumors is unknown, but the cause may be an abnormal tumor suppressor gene.
Zollinger-Ellison syndrome usually occurs in people between ages 30 and 60.
www.stopgettingsick.com /Conditions/condition_template.cfm/2685/316/1   (301 words)

  
 Basic Summary for Zollinger-Ellison syndrome - WrongDiagnosis.com
Brief description of Zollinger-Ellison syndrome: Rare syndrome with multiple digestive or pancreas tumors.
Profile for Zollinger-Ellison syndrome: Zollinger-Ellison syndrome usually occurs in people between ages 30 and 60.
Causes of Zollinger-Ellison syndrome: What causes people with Zollinger-Ellison syndrome to develop tumors is unknown, but the cause may be an abnormal tumor suppressor gene.
www.wrongdiagnosis.com /z/zollinger_ellison_syndrome/basics.htm   (208 words)

  
 Zollinger-Ellison syndrome
Doctors don't know exactly what causes Zollinger-Ellison syndrome.
In a nuclear scan, radioactive substances introduced into your body permit a gamma camera to detect tumors.
Your doctor may also suggest severing the nerves that promote acid secretion in your stomach.
cnnstudentnews.cnn.com /HEALTH/library/DS/00461.html   (1223 words)

  
 IngentaConnect A randomized controlled crossover study comparing synthetic porci...   (Site not responding. Last check: 2007-11-06)
Although biologically-derived porcine secretin is approved for the diagnosis of Zollinger–Ellison Syndrome, it is no longer available in the United States.
In the current study we compared secretin testing results in six confirmed Zollinger–Ellison Syndrome patients using the biologically-derived product and both synthetic products (human and porcine) in a three-way, randomized, single-blind Latin-squares crossover study.
Statistically significant changes from baseline occurred at 1, 2 and 5 min for biologically-derived porcine secretin and at 2 and 5 min for both synthetic porcine and synthetic human secretin, in keeping with the expected time curve for positive tests.
api.ingentaconnect.com /content/bsc/apt/2001/00000015/00000005/art00976   (317 words)

  
 Clinical Study: 90-DK-0137, Evaluation of the Gastrinoma in Patients with Zollinger-Ellison Syndrome   (Site not responding. Last check: 2007-11-06)
This protocol concerns the approach to the localization, diagnosis of MEN1 and management of the tumor and the tissue samples in patients with Zollinger-Ellison syndrome.
It details the diagnostic imaging tests to be used to localize the tumor, investigations for MEN1 the subsequent management of the tumor and tissue samples for research.
New patients will be evaluated initially as described in the protocol entitled, "Diagnostic evaluation of patients with suspected abnormalities of gastric secretion" (89-DK-0005).
clinicalstudies.info.nih.gov /detail/A_1990-DK-0137.html   (194 words)

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