
	Where results make sense

Topic: Zona reticularis

In the News (Thu 31 Dec 09)

Northern Trust

Marvin Harrison

Peter Chernin

Gary Locke

Match Play

Penelope Cruz

Mickey Rourke

AR Rahman

Danny Boyle

Hugh Jackman

	Adrenal cortex - Wikipedia, the free encyclopedia
		Beneath the glomerulosa are the zonae fasciculata and reticularis, which produce glucocorticoids (eg, cortisol) and weak androgens (eg, dehydroepiandrosterone).
		The innermost layer of the adrenal cortex, the zona reticularis sits beneath the zona fasciculata and atop the adrenal medulla.
		It is thought that the zona reticularis is the principal source of glucocorticoids and adrenal androgens, with the zona fasciculata activating only after prolonged stimulation.
	en.wikipedia.org /wiki/Adrenal_cortex (623 words)

	Zona reticularis in aging spontaneously hypertensive rats: a quantitative ultrastructural study of 70- and 95-week-old ... (Site not responding. Last check: 2007-11-01)
		Zona reticularis in aging spontaneously hypertensive rats: a quantitative ultrastructural study of 70- and 95-week-old animals.
		The zona reticularis of 70- and 95-week-old female Wistar-Kyoto (WKY) and spontaneously hypertensive (SH) rats was studied by quantitative stereologic techniques.
		The zona reticularis in the adrenal gland of 70-week-old SH rats was virtually identical to that of 70-week-old WKY rats.
	www.arclab.org /medlineupdates/abstract_525678.html (240 words)

	Slide: Adrenal : Histology \| Webpathology.com (Site not responding. Last check: 2007-11-01)
		Zona reticularis lies deep to zona fasciculata and abuts on the medulla in the head and body of the gland.
		Cells are arranged in anastomosing cords and have acidophilic granular cytoplasm and round vesicular nuclei with punctate nucleoli.
		Zona reticularis is responsible for glucocorticoid and sex hormone synthesis.
	www.webpathology.com /image.cfm?n=4&Case=78 (48 words)

	ENDOCRINE GLANDS
		zona glomerulosa is the thin outermost zone where the cells are arranged as ovoid groups or arching cords.
		zona fasciculata is the thick middle zone in which the cells are arranged in radial cords, 1-2 cells thick.
		zona reticularis is the innermost zone characterized by anastomosing cords of cells.
	www.mc.vanderbilt.edu /histology/labmanual2002/labsection3/AdrenalGlands03.htm (805 words)

	Endotext.com - Adrenal Physiology And Diseases, Adrenal Androgens
		The adrenal cortex is divided into three histologic and functional zones: the outer, aldosterone-secreting, called zona glomerulosa; the intermediate, cortisol-secreting, zona fasciculata; and the inner, androgen-secreting zona reticularis.
		Whereas the zona glomerulosa is primarily regulated by angiotensin II, both the zona fasciculata and the zona reticularis are regulated by corticotropin (ACTH) (1).
		The mechanism(s) by which the zona reticularis develops with age and the regulation of adrenarche onset are notunderstood.
	www.endotext.org /adrenal/adrenal3/adrenal3.htm (2678 words)

	Control of adrenal cell proliferation by AT1 receptors in response to angiotensin II and low-sodium diet -- McEwan et ...
		Proliferation of nonepithelial cells was not affected by ANG II or losartan in the zona glomerulosa, zona reticularis, or the
		and the zona glomerulosa was wider as a consequence (Figs.
		An ultrastructural stereological study of the effects of angiotensin II on the zona glomerulosa of the rat adrenal cortex.
	ajpendo.physiology.org /cgi/content/full/276/2/E303 (3399 words)

	Steroid Hormones
		Zona glomerulosa cells are unique in the adrenal cortex in containing the enzyme responsible for converting corticosterone to aldosterone, the principal and most potent mineralocorticoid.
		The result is that the zona glomerulosa is mainly responsible for the conversion of cholesterol to the weak mineralocorticoid, corticosterone and the principal mineralocorticoid, aldosterone.
		Zona fasciculata and zona reticularis cells also contain the 17-20 lyase, whose activity is responsible for producing the androgens, dehydroepiandosterone and androstenedione.
	dwb.unl.edu /Teacher/NSF/C11/C11Links/web.indstate.edu/thcme/mwking/steroid-hormones.html (1789 words)

	Home Page
		The transition from the zona fasciculata to zona reticularis is gradual: the cells in the lower part of the ZF are smaller and darker than the spongiocytes.
		For example, the medulla may be missing and the zona reticularis on one side may go directly into the ZR on the other side.
		In the cortex, the lighter zona fasciculata is bordered by the darker zona glomerulosa and zona reticularis (fairly large in the section shown here).
	courseweb.edteched.uottawa.ca /medicine-histology/English/Endoctrine/Default.htm (4972 words)

	Adrenal Histology \| Webpathology.cfm (Site not responding. Last check: 2007-11-01)
		Zona glomerulosa (just beneath the capsule) is the site of aldosterone synthesis and responds to angiotensin and potassium.
		Remarks: Zona fasciculata lies between zona glomerulosa (beneath capsule) and zona reticularis (deep).
		Remarks: Zona reticularis lies deep to zona fasciculata and abuts on the medulla in the head and body of the gland.
	www.webpathology.com /case.cfm?case=78 (157 words)

	Steroids and hormones
		Zona glomerulosa is the outer layer of cells whereas zona reticularis is in contact with medulla.
		Zona faciculata is sandwiched between zona glomerulosa and zona faciculata.
		Aldosterone is synthesized in zona glomerulosa where as glucocorticoids (cortisol) and androgens are synthesized in zona faciculata and zona reticularis.
	w3.ouhsc.edu /dentalbiochemistry/madhu/HORMONES.htm (2430 words)

	Zona Virus -- Recommendations and Resources (Site not responding. Last check: 2007-11-01)
		The zona pellucida is a glycoprotein matrix surrounding the plasma membrane of a mammalian oocyte.
		The zona glycoprotein, ZP3, is responsible for sperm binding, adhering to proteins on the sperm plasma membrane.
		Zona da Mata was the richest region of Minas Gerais from the 1850's to the 1930's, due the big production of coffee and milk.
	www.becomingapediatrician.com /health/185/zona-virus.html (1109 words)

	[No title] (Site not responding. Last check: 2007-11-01)
		Note the investing connective tissue capsule of the gland, The zona glomerulosa is not well delineated here, but the zona fasciculata is depicted here as the light staining band between the pink staining capsule and the eosinophilic pink staining zone of the reticulatis.
		The demarcation between zona fasciculata and zona reticularis is not evident in this slide.
		The zona glomerulosa is on the right and the zona reticularis is at the left.
	www.georgetown.edu /dml/educ/micro/thyroid/thyroid.txt (982 words)

	delta 4-Hydrogenase in guinea pig adrenal: evidence of localization in zona reticularis and age-related change.
		In this paper we show that delta 4-hydrogenase is localized in the zona reticularis and increases coincidently with the large increase in the volume of this zone with age.
		Again, only those which contained zona reticularis cells, that is, those from the inner cortices, had activity.
		The activity was shown to be present in both microsomes and cytosol, although the latter was preferentially expressed in a 15,000 X g supernatant.
	www.arclab.org /medlineupdates/abstract_7075535.html (258 words)

	[No title]
		Function, regulation, and significance of: Cholesterol esterase: cholesterol esterase catalyzes the conversion of cholesterol ester to cholesterol in the cytoplasm, and is activated by angiotensin II (via Gq) in the zona glomerulosa or by ACTH (via Gs) in the zona fasciculata/reticularis.
		P-450scc: P-450scc cleaves cholesterol to produce pregnenolone on the inner mitochondrial membrane, and is activated by angiotensin II (via Gq) in the zona glomerulosa or by ACTH (via Gs) in the zona fasciculata/reticularis.
		Synthesis of aldosterone in the zona glomerulosa: synthesized from pregnenolone conversion to progesterone (via 3(-OHSD and (5,4 isomerase) followed by conversion to 11-DOC (via 21-hydroxylase) and final conversion to aldosterone (via 11(-hydroxylase and 18-hydroxylase) Enzyme specific to zona glomerulosa: 18-hydroxylase Enzyme specific to zona fasiculata/reticularis: 17-hydroxylase 3.
	www.u.arizona.edu /~ajgulbis/MedLinks/Biochemistry/BiochemistryType/48.doc (367 words)

	[No title]
		zona reticularis - where many of the androgens are thought to be made.
		ACTH circulates and stimulates the zona fasiculata and zona reticularis to produce cortisol.
		One of the reasons that the zona glomerulosa (ZG) so specifically produces aldosterone is that the ZG does not have the ability to 17 hydroxylase.
	www.uhmc.sunysb.edu /som/students/2001/noteservice/e5.doc (3153 words)

	Lupron vs. Lysodren (Site not responding. Last check: 2007-11-01)
		The middle zone is the zona fasciculata (it comprises about 70% of the cortex), and it secretes the glucocorticoid hormones (mainly cortisol).
		The inner zone is the zona reticularis, and it secretes the sex steroids (estrogens, progestins, testosterone) and the androgens (DHEA,and Andro.).
		In a histopath (biopsy) study in dogs, the zona fasciculata was destroyed in the hyperplasia group, but the tumor group contained a clear description of the tumor histology.
	www.miamiferret.org /fhc/murray.htm (1185 words)

	Laboratory Sixteen: Endocrine System
		The cortex is subdivided into three zones (zona glomerulosa, zona fasciculata, zona reticularis) of steroid producing cells.
		The cells of the zona fasciculata are arranged in rows separated by long sinusoids.
		The zona reticularis has cells that are smaller and eosinophilic.
	medinfo.ufl.edu /year1/histo/review/lab16.html (1243 words)

	Phys. I, Sect. 6, Adrenal Cortex, Syllabi (Site not responding. Last check: 2007-11-01)
		Zona fasciculata is the middle and widest layer.
		Conditions that increase the output of aldosterone and cause hypertophy of the zona glomerulosa have no effect on the other two layers.
		Conversely, factors that cause increase secretion of cortisol and adrenal androgens and cause hypertophy of the zona’s fasciculata an reticularis have little or no effect on the zona glomerulosa.
	www.hodsonhome.com /mna2001/physiology/physiology1/phy1sec6adrenalcortex.htm (1878 words)

	Changes in the glomerulosa cell phenotype during adrenal regeneration in rats -- Engeland and Levay-Young 276 (5): 1374 ...
		zona glomerulosa and an inner zona fasciculata/reticularis (8).
		whereas the synthesis of corticosterone by fasciculata and reticularis
		of regeneration, proliferation is not restricted to the zona intermedia.
	ajpregu.physiology.org /cgi/content/full/276/5/R1374 (4024 words)

	Ed's Histology Notes: Adrenal, Kidney, Bladder
		The zona glomerulosa is considered responsible for making aldosterone (your great mineralocorticoid, for hanging onto sodium and wasting potassium) under the influence of ACTH (corticotropin), angiotensin II, and probably a third yet-unknown hormone (I'll tell you why I believe this in "Path").
		The zona fasciculata has cords ("fascicles" means "bundles", ask Mussolini or anyone using the word "fascist" in contemporary rhetoric) one or two cells thick ("can't be three, each cell needs to be adjacent to a capillary").
		The zona reticularis is credited with producing dehydroepiandrosterone, a sex hormone that works much like testosterone, and is responsible for women's body-hair and libidos.
	www.pathguy.com /urinehis.htm (2777 words)

	e6c (Site not responding. Last check: 2007-11-01)
		The zona reticularis is the innermost layer of the adrenal cortex; its main function is to produce sex steroids.
		Males produce large amounts of testosterone in the testes, so the androgens produced by the zona reticularis are converted to estrogen in the blood.
		In the female, androgens secreted by the zona reticularis are a primary source of testosterone.
	www.vet.purdue.edu /depts/bms/nour/production/Physiology/endocrine/e6c.htm (127 words)

	Steroid Hormones
		The adrenal cortex is composed of 3 main tissue regions: zona glomerulosa, zona fasciculata, and zona reticularis.
		Cells of the zona fasciculata and zona reticularis lack aldosterone synthase (P450c18) that converts corticosterone to aldosterone, and thus these tissues produce only the weak mineralocorticoid corticosterone.
		Zona fasciculata and zona reticularis cells also contain the C17,20 lyase, whose activity is responsible for producing the androgens, dehydroepiandosterone (DHEA) and androstenedione.
	www.indstate.edu /thcme/mwking/steroid-hormones.html (2517 words)

	Adrenarche - Wikipedia, the free encyclopedia
		Structural changes of adrenarche include increased size and mass of the adrenal cortex, and completion of differentiation into the three zones: zona glomerulosa, zona fasciculata, and zona reticularis.
		One of the primary functional changes is further differentiation of sex steroid synthesis among the three zones, so that as in adults, the zona glomerlulosa primarily produces mineralocorticoids such as aldosterone, the zona fasciculata primarily produces glucocorticoids such as cortisol, and the zona reticularis primarily produces androgens such as dehydroepiandrosterone, dehydroepiandrosterone sulfate, and androstenedione.
		The second important functional change is a steady increase over several years in the daily production of adrenal androgens.
	en.wikipedia.org /wiki/Adrenarche (798 words)

	Premature Adrenarche--Normal Variant or Forerunner of Adult Disease? -- Ibáñez et al. 21 (6): 671 -- ...
		DHEAS, emanate chiefly from the zona reticularis (36, 37, 38).
		Relation of plasma DHEAS to growth of the zona reticularis and increase in adrenal volume with age.
		to the maturation of the zona reticularis as observed in the
	edrv.endojournals.org /cgi/content/full/21/6/671 (8914 words)

	Endocrine Introduction (Site not responding. Last check: 2007-11-01)
		The cortex is composed of three layers (zones) of cells (deep to superficial): zona reticularis (zone nearest the adrenal medulla), zona fasiculata, and the zona glomerulosa (closest to the connective tissue capsule that holds the adrenal glands together).
		The zona glomerulosa secretes mineralcorticoids such as aldosterone that regulates the ionic composition of the urine produced by the kidneys.
		The zona reticularis secretes some glucocorticoids and some androgens (male sex steroids) such as DHEA (dehydroepiandrosterone) in both sexes.
	www.biosbcc.net /barron/physiology/endo/adren.htm (606 words)

	eMedicine - 3-Beta-Hydroxysteroid Dehydrogenase Deficiency : Article Excerpt by: J Paul Frindik, MD
		Pathophysiology: Anatomically, the adrenal gland can be divided into 3 zones, (1) the zona glomerulosa, which produces predominately mineralocorticoid, (2) the zona fasciculata, which produces predominately glucocorticoid, and (3) the zona reticularis, which produces predominantly androgens.
		Think of the zona glomerulosa and the zonae fasciculata and reticularis as 2 separate endocrine organs because they are under separate control.
		By contrast, cortisol synthesis and secretion is regulated by adrenocorticotrophic hormone (ACTH), which stimulates the enzyme P-450scc (20,22 desmolase) with subsequent increased production of all adrenal steroids in both the zona fasciculata and the zona reticularis (see Image 1).
	www.emedicine.com /ped/byname/3-beta-hydroxysteroid-dehydrogenase-deficiency.htm (598 words)

	Blue Histology - Endocrines
		The zona glomerulosa is not influenced by ACTH.
		The zona fasciculata consists of radially arranged cell cords separated by fenestrated sinusoid capillaries.
		Both the zona fasciculata and zona reticularis depend on ACTH to sustain their function and survival.
	www.lab.anhb.uwa.edu.au /mb140/CorePages/Endocrines/endocrin.htm (3168 words)

	Normal Physiology
		The adrenal cortex is composed of an three zones: the zona glomerulosa which produces aldosterone, the middle portion, the zona fasciculata which produces cortisol and androgens, and the inner most layer the zona reticularis, which produces cortisol and androgens.
		The zona fasciculata and reticularis have the enzyme, 17 alpha hydroxylase which is necessary for conversion of precursors to cortisol and androgens.
		is formed in the cells of the zona glomerulosa from cholesterol by converting corticosterone to aldosterone.
	education.vetmed.vt.edu /Curriculum/VM8094/gct/Charlie/Physio.html (510 words)

	[No title]
		The outer zone called the zona glomerulosa consists of columnar cells that are packed in ovoid or spherical groups beneath the capsule.
		The middle zone is the most prominent part of the cortex and is called the zona fasciculata.
		The medullary tissue alone is oxidized to a yellowish brown color due to the presence of catecholamine hormones in its cells.
	www.georgetown.edu /dml/educ/hist/lab17/lab17old.txt (1245 words)

Try your search on: Qwika (all wikis)