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| | Vanita, Mol Vis 2006; 12:518-522. |
 | | Congenital cataract is a common, major abnormality of the eye that causes nearly one-third of childhood blindness. |
 | | Thus, in cataract, one major gene seems to be affected, but variants in other genes involved in development, growth, and maintenance of lenses might modify its pathogenesis, explaining the poor correlation between a particular phenotype and the affected gene involved in human and mouse cataracts [26]. |
 | | Based on tight association of cataract and microcornea in the present family, and on the basis of expression of CRYAA in the anterior eye segment as well, it appears that apart from the lens, αA-crystallins might also play a role in the normal development of the anterior segment of the eye. |
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