| |
| | Cadmium (CASRN 7440-43-9), IRIS, Environmental Protection Agency |
 | | Four studies of workers exposed to cadmium dust or fumes provided evidence of a statistically significant positive association with prostate cancer (Kipling and Waterhouse, 1967; Lemen et al., 1976; Holden, 1980; Sorahan and Waterhouse, 1983), but the total number of cases was small in each study. |
 | | Exposure of Wistar rats by inhalation to cadmium as cadmium chloride at concentrations of 12.5, 25 and 50 ug/cu.m for 18 months, with an additional 13-month observation period, resulted in significant increases in lung tumors (Takenaka et al., 1983). |
 | | Cadmium treatment in vivo or in vitro appears to interfere with spindle formation and to result in aneuploidy in germ cells of mice and hamsters (Shimada et al., 1976; Watanabe et al., 1979; Gilliavod and Leonard, 1975). |
| www.epa.gov /iris/subst/0141.htm (1811 words) |
|