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Topic: Growth hormone treatment

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	PCRM >> Research >> Ethics in Human Research >> Concerns About Growth Hormone Experiments ...
		Slight elevations of growth hormone, with corresponding increases in IGF-1, may be one reason why tall women have a higher risk of breast cancer, compared to shorter women.
		A controlled trial of methionyl growth hormone therapy in prepubertal children with short stature, subnormal growth rate and normal growth hormone response to secretagogues.
		Effects of two years of methionyl growth hormone therapy in two dosage regimens in prepubertal children with short stature, subnormal growth rate, and normal growth hormone response to secretagogues.
	www.pcrm.org /resch/humres/growthhormone.html (1889 words)

	(Holtorf Medical Group, Inc - Torrance, CA) Treatment with Human Growth Hormone
		Growth Hormone diminishes rapidly after the age of 30 and it is this rapid decline that results in many negative aspects of aging, including increased body fat, decreased muscle mass, increased wrinkles, cancer, and heart disease.
		The administration of human growth hormone for six months was accompanied by an 8.8 % increase in lean body mass, a 14.4 % decrease in adipose-tissue mass, and a 23.2% improvement in overall body composition.
		Conclusion of the study’s authors: Diminished secretion of growth hormone is responsible in part for the decrease of lean body mass, the expansion of adipose-tissue mass (fat), and the thinning of the skin that occur in old age.
	www.hormoneandlongevitycenter.com /growthhormone/view.nhtml?profile=growthhormone&UID=10015 (813 words)

	HGF - Growth Hormone Deficiency (Site not responding. Last check: 2007-11-02)
		Growth hormone is a protein that is produced by the pituitary ("master") gland and is vital for normal growth.
		Growth hormone deficiency is moderately difficult to diagnose because the pituitary gland produces growth hormone in bursts.
		One way of testing for growth hormone deficiency is to give the child a substance that causes the release of a growth hormone burst in normal children and measure the amount of growth hormone present in several blood samples obtained over a period of time.
	www.hgfound.org /growth.html (2311 words)

	Growth Hormone Deficiency - Treatment Options - Conditions & Treatments - DrugDigest
		The primary goal of treatment of GHD in children is to restore growth hormone to typical levels so the child can grow to a normal height.
		Growth hormone must be supplemented or replaced by using synthetic (artificially made) growth hormone, which is made through recombinant DNA technology.
		Children with GHD are typically treated with supplemental synthetic growth hormone for a number of years until they either have reached an acceptable height for their age or have reached their maximum growth potential.
	www.drugdigest.org /DD/HC/Treatment/0,4047,550489,00.html (512 words)

	Growth Problems
		People who have constitutional growth delay are often referred to as "late bloomers." If a doctor suspects constitutional growth delay in a kid or teen, he or she might take X-rays of bones and compare them with X-rays of what's considered average for their age.
		Growth hormone deficiency usually affects only one person in a family and isn't generally passed on from parents to children.
		Recently, growth hormone treatment has been approved for some kids and teens who are not growth hormone deficient but who appear to be headed for a very short adult height (under 5 feet, 4 inches [1.6 meters] for boys and under 4 feet, 11 inches [1.5 meters] for girls).
	kidshealth.org /teen/diseases_conditions/growth/growth_hormone.html (1579 words)

	Study Of Growth Hormone Treatment And Creutzfeldt-Jakob Disease Underscores Need For Prevention Of Adrenal Crises
		Growth hormone deficiency results from a failure of the pituitary gland to make sufficient amounts of the hormone, explained the study's principal author, James L. Mills, M.D., chief of the Pediatric Epidemiology Section of the National Institute of Child Health and Human Development (NICHD).
		Growth hormone is also needed to maintain normal blood sugar; its absence may result in potentially fatal drops in blood sugar (hypoglycemia).
		The study authors noted that patients who lacked only growth hormone and had no underlying medical problem but produced normal amounts of other pituitary hormones had a death rate that was comparable to what would be expected in a general population of people in the same age group.
	advancetherapynetwork.com /news/growth-hormone-study.html (1458 words)

	Metabolism.com - Should Adults Receive Growth Hormone Treatment?
		The decline in growth hormone levels with aging is mirrored by a decline in a host of other critical substances which maintain our health, such as DHEA (from the adrenal gland).
		Growth hormone deficient adults are given significantly smaller doses of growth hormone as compared to children being treated to achieve normal height.
		Receiving treatment with growth hormone or testosterone without a prescription from a licensed professional is illegal, as is receiving treatment with these hormones for the sole purpose of enhancing athletic performance.
	www.metabolism.com /news/2003-10-25 (1234 words)

	HGF - Growth Hormone Treatment (Site not responding. Last check: 2007-11-02)
		A doctor's recommendation to begin a child on growth hormone (GH) is based on consideration of many factors, including a complete evaluation of the child's growth pattern, general health, medical and family history, and results of laboratory tests.
		GH promotes the growth of muscle and bones, while the shift of lipid metabolism tends to be in the opposite direction.
		The overall psychological effects of GH therapy are positive; an increased growth rate, more mature appearance and the hope for an adult height within the normal range are viewed as positive by both parents and children.
	www.hgfound.org /growthhormone.html (1442 words)

	Human Growth Hormone - Symptoms, Treatment and Prevention
		Growth hormone, as the name implies, is essential for the growth and development of babies and children.
		Growth hormone deficiency, whether alone or in association with other abnormalities, is hereditary in about 10 percent of all cases.
		Growth deficiency in adulthood tends to cause mild to moderate obesity, weakness (asthenia), and reduced cardiac output.
	www.healthscout.com /ency/1/68/main.html (1145 words)

	Growth Hormone Treatment Benefits Adult Patients
		Growth hormone deficiency in children is a rare condition that results in stunted growth.
		While a synthetic version of the naturally-occurring hormone can be used to treat growth hormone deficiency, there have been few studies looking at the effectiveness of the drug in adult patients after 18 months of treatment.
		And individuals on growth hormone replacement had an improvement in energy levels and psychological well-being, while there was no change in the untreated group, according to the report.
	www.personalmd.com /news/a1999090603.shtml (301 words)

	Product Abstract:Growth Hormone (Gh)
		Effects of 12 months of growth hormone (GH) treatment on calciotropic hormones, calcium homeostasis, and bone metabolism in adults with acquired GH deficiency: a double blind, randomized, placebo-controlled study.
		Growth hormone enhances renal tubular phosphate reabsorption and 1,25-dihydroxy-cholecalciferol production in normal and in GH deficient individuals, and may thus be of benefit to patients with familial hypophosphataemic rickets.
		Growth hormone improved cardiac output, particularly during exercise (from 7.4+/-0.7 to 9.7+/-0.9 liters per minute, P=0.003), and enhanced ventricular work, despite reductions in myocardial oxygen consumption (from 56+/-6 to 39+/-5 ml per minute, P=0.005) and energy production (from 1014+/-100 to 701+/-80 J per minute, P=0.002).
	www.lef.org /prod_hp/abstracts/php-ab356.html (3296 words)

	Growth Hormone Treatment in Prader-Willi Syndrome
		Prior to giving the growth hormone measurements were made of height and weight and the amount of body fat was assessed by a number of means including, some of the most up-to-date techniques for accurately assessing body fat in children.
		Basically, this means that the growth in height was greater during the period of growth hormone administration than would be found in non-affective children of the same age.
		The administration in growth hormone is not without side-effects and potential risks however, I believe that there is a body of evidence accumulating that would suggest the time has come for it to be considered as a serious treatment therapy in Prader-Willi syndrome.
	www.pwsa-nz.co.nz /artght.html (575 words)

	APEG Position Paper - Growth Hormone Treatment In Children And Adolescents (Site not responding. Last check: 2007-11-02)
		Children with growth hormone deficiency require close monitoring for the symptoms of SCFE, most commonly pain in the hip or knee, or a limp.
		Recently, a long-term follow-up study of growth hormone deficient patients treated as children with growth hormone extracted from human pituitary glands, reported a very small but statistically significant increase in the incidence of bowel cancer compared with the general population.
		The current evidence is not sufficiently strong to advise against growth hormone treatment in children for whom it is expected to be of benefit.
	www.racp.edu.au /apeg/ght.htm (939 words)

	Novo Nordisk UK - Treating growth disorders
		Some growth hormone comes as a powder and in order to give it as an injection it needs to be mixed with a liquid (called a solvent or diluent) to make a solution.
		As with other hormones, there is a daily rhythm of growth hormone release from the pituitary gland into the bloodstream, with the largest amount released in the early night-time hours during deep sleep.
		During travel it is advisable to carry your growth hormone in a cool bag and to put it in a fridge once you arrive at your destination.
	www.novonordisk.co.uk /documents/article_page/document/HGH_Treating_growth_disorders.asp (984 words)

	Growth Hormone Deficiency (Site not responding. Last check: 2007-11-02)
		Growth hormone deficiency, as the name implies, is the absence or deficiency of growth hormone produced by the pituitary gland to stimulate the body to grow.
		Growth hormones are produced by the pituitary gland, which is attached to the hypothalamus (a part of the brain that affects the pituitary gland) located at the base of the brain.
		Until the 1980s, the only source of human growth hormone was from the pituitary glands of deceased people, where an increased chance of transmission of human diseases from human growth hormone existed.
	www.stlouischildrens.org /tabid/88/itemid/2652/Growth-Hormone-Deficiency.aspx (797 words)

	AEGiS-BBC: Growth hormone treatment for HIV
		In the study five male HIV patients were given daily doses of growth hormone.
		The researchers say this is the first study to show how the thymus functions can be significantly enhanced by growth hormone therapy to stimulate it to produce new T cells.
		Doctors added that the study was only preliminary, and was not intended to show whether growth hormone actually improved the health status of the patients.
	www.aegis.com /news/bbc/2002/BB020730.html (773 words)

	Sex Change in Cytochrome P-450 Phenotype by Growth Hormone Treatment of Adult Rat Hepatocytes Maintained in a Culture ...
		Results of studies of hypophysectomized rats suggest that growth hormone serves as a final common mediator through which gonadal steroids and other modifiers of pituitary function alter the expression of gender-specific liver genes such as the sexually dimorphic pair of cytochrome P-450 isozymes, male-specific P-450h and female-specific P-450i.
		We tested the effects of growth hormone in a system for primary monolayer culture of adult rat hepatocytes on a laminin-rich extracellular matrix (matrigel), which permits sustained expression of both constitutive and inducible liver genes in a chemically defined medium.
		We conclude that the somatogenic effects of growth hormone acting alone and directly on the hepatocyte in culture are sufficient to ``feminize'' the cytochrome P-450 phenotype.
	www.pnas.org /cgi/content/abstract/85/24/9783 (584 words)

	BioMed Central \| Full text \| Motives for choosing growth-enhancing hormone treatment in adolescents with idiopathic ...
		Although height gain is an obvious measure for evaluating hormone treatment, this may not be the ultimate goal for the person, but rather a means to reach other goals such as the amelioration of current height-related psychosocial problems or the enhancement of future prospects in life and society.
		Although height gain is an obvious measure for evaluating hormone treatment, this may not be the ultimate goal of the person, but rather a means to reach other goals such as to ameliorate current height-related psychosocial problems or to enhance future prospects in life and society.
		Before treatment, and at one, two, and three years after beginning the treatment, the adolescents and the parents of both the treatment and control groups filled out questionnaires to assess the psychosocial functioning of the adolescents.
	www.biomedcentral.com /1471-2431/5/15 (5339 words)

	Human Growth Hormone (Site not responding. Last check: 2007-11-02)
		Growth hormone is the pituitary secreted hormone that is responsible for the growth of a child to a full sized mature adult.
		Growth hormone therapy will keep your bones dense and strong, and will reduce the likelihood of future osteoporosis; and will improve cognitive functions, and is even likely to lessen the likelihood of certain dementias and other cognitive ailments.
		Human growth hormone is a pituitary released hormone that is responsible for the growth of a child to a mature and full sized adult.
	www.briangreens.com (8772 words)

	Humatrope Therapy in India, Growth Hormone Treatment, Turner Syndrome Treatment in India.
		Growth hormone deficiency, thyroid hormone deficiency, and excessive cortisol production are possible hormonal causes of slow growth that are treatable.
		Humatrope is indicated for the long-term treatment of pediatric patients who have growth failure due to an inadequate secretion of normal endogenous growth hormone.
		Humatrope is indicated for the treatment of short stature associated with Turner syndrome in patients whose epiphyses are not closed.
	www.lillyindia.co.in /humatrope/index.cfm (257 words)

	Growth Hormone Deficiency
		Growth hormone deficiency, as the name implies, is the absence or deficiency of growth hormone produced by the pituitary gland to stimulate the body to grow.
		Growth hormones are produced by the pituitary gland, which is attached to the hypothalamus (a part of the brain that affects the pituitary gland) located at the base of the brain.
		Treatment usually lasts several years, although results are often seen as soon as three to four months after the injections are started.
	www.muschealth.com /gs/HealthTopic.aspx?action=showpage&pageid=P01952 (743 words)

	Growth Hormone Deficiency (Site not responding. Last check: 2007-11-02)
		Growth hormone deficiency, as the name implies, is the absence or deficiency of growth hormone produced by the pituitary gland to stimulate the body to grow.
		Growth hormones are produced by the pituitary gland, which is attached to the hypothalamus (a part of the brain that affects the pituitary gland) located at the base of the brain.
		Treatment usually lasts several years, although results are often seen as soon as three to four months after the injections are started.
	www.healthsystem.virginia.edu /uvahealth/peds_diabetes/ghd.cfm (742 words)

	Child Growth Foundation GHD
		Growth Hormone Deficiency (GHD) is generally due to the pituitary gland being unable to produce sufficient GH to generate the growth process.
		GHD does not affect intrauterine growth, at least to an extent measurable by birth weight or length, but from the second year of life growth is slower than normal and occasionally growth failure commences from birth.
		Growth hormone deficiency can also result from damage to the part of the brain controlling the pituitary gland, the pituitary itself, or both.
	www.childgrowthfoundation.org /ghd.htm (856 words)

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