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Topic: Hypercholesterolemia

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	Hypercholesterolemia - Wikipedia, the free encyclopedia
		Hypercholesterolemia (literally: high blood cholesterol) is the presence of high levels of cholesterol in the blood.
		Classically, hypercholesterolemia was categorized by lipoprotein electrophoresis and the Fredrickson classification.
		If the hypercholesterolemia is hereditary (familial hypercholesterolemia), there is often a family history of premature, earlier onset atherosclerosis, as well as familial occurrence of the signs mentioned above.
	en.wikipedia.org /wiki/Hypercholesterolemia (1332 words)

	Hypercholesterolemia
		Hypercholesterolemia is a condition in which levels of cholesterol in the blood are higher than normal.
		Hypercholesterolemia can also be an inherited problem that affects the way the body processes cholesterol.
		Hypercholesterolemia can also be caused by any disease that raises LDL cholesterol levels, such as diabetes mellitus, kidney disease, liver disease, or hypothyroidism.
	www.hmc.psu.edu /healthinfo/h/hypercholesterolemia.htm (581 words)

	Hypercholesterolemia - familial hypercholesterolemia
		On the other hand, and though less dramatic than the many cardiovascular familial hypercholesterolemia bilirubin procedures, some people, especially with newer and more sophisticated information, are changing their eating and especially food supplement patterns, many of the supplements still being prescription agents.
		Evidence genetic hypercholesterolemia natural cure is accumulating that eating more carbohydrates - especially simpler, more refined carbohydrates - increases levels of triglycerides in the blood, lowers HDL, and may shift the LDL particle distribution pattern, even though not elevated, into unhealthy blood transport, atheroma-stimulating patterns.
		There diabetes hypercholesterolemia are those that claim that cholesterol itself is a healthy nutrient and that the whole "lipid hypothesis", hypercholesterolemia on canines which links cholesterol with heart disease and atherosclerosis, is incorrect, despite vast research linking elevated cholesterol levels to poor outcomes.
	www.medicalgeo.com /Med-Diseases-Ho---Hy/Hypercholesterolemia.html (1198 words)

	eMedicine - Hypercholesterolemia, Polygenic : Article by William L Isley
		Hypercholesterolemia is more common in individuals with a family history of the condition, but lifestyle factors (eg, a diet high in saturated fat) clearly play a major role.
		Secondary hypercholesterolemia is suggested by stigmata of liver disease, hypothyroidism, hypopituitarism, nephrotic syndrome, and chronic renal disease.
		Several drugs and disease states are associated with hypercholesterolemia; however, for the overwhelming majority of patients, the Western lifestyle of a high-fat diet superimposed on a susceptible genotype appears to cause hypercholesterolemia.
	www.emedicine.com /med/topic1073.htm (9205 words)

	Hypercholesterolemia Information on Healthline
		Hypercholesterolemia refers to levels of cholesterol in the blood that are higher than normal.
		Hypercholesterolemia is diagnosed by using a blood test.
		Persons with hypercholesterolemia are at high risk of dying from heart disease or stroke.
	www.healthline.com /galecontent/hypercholesterolemia (1002 words)

	Hypercholesterolemia definition - Cholesterol: health and medical information about high cholesterol and heart disease
		Familial hypercholesterolemia is the most common inherited type of hyperlipidemia (high lipid levels in blood).
		Persons with familial hypercholesterolemia can reduce their risk by adhering to a very low cholesterol diet under a doctor's supervision, and may also need to take medications that reduce their cholesterol level.
		Familial hypercholesterolemia is due to a genetic defect in the receptor (the dock on the surface of cells) for LDL (low density lipoprotein).
	www.medterms.com /script/main/art.asp?articlekey=3835 (213 words)

	Whitehead Institute - Hypercholesterolemia
		(Aug. 28, 1996) — Familial hypercholesterolemia, a genetic disease characterized by high levels of cholesterol and early mortality, is caused by defects in the receptor for the low-density lipoprotein (LDL)—the bad cholesterol.
		In most cases of familial hypercholesterolemia, this happens because the gene for the LDL receptor is slightly mutated.
		Familial hypercholesterolemia (FH) is an autosomal dominant trait, meaning that a child born to an affected parent has a 50 percent chance of inheriting the gene.
	www.wi.mit.edu /news/archives/1996/pk_0828.html (688 words)

	Genomics\|HuGENet\|Reviews\|Familial hypercholesterolemail, PAD & stroke\|PubMed ID: 15321839
		Heterozygous familial hypercholesterolemia (FH) is an autosomal dominant disorder known to be associated with elevated cholesterol levels and increased risk of premature coronary heart disease.
		Better understanding of the association between FH and the incidence of ischemic stroke events could have a public health impact by improving the diagnosis, prognosis, and treatment of individuals with FH and their relatives and by elucidating the relation between cholesterol levels and ischemic cerebrovascular disease.
		Familial hypercholesterolemia (FH) is an autosomal dominant disorder affecting approximately one of 500 Caucasians (1).
	www.cdc.gov /genomics/hugenet/reviews/FHStroke.htm (4356 words)

	eMedicine - Hypercholesterolemia, Familial : Article by Elena Citkowitz
		Familial hypercholesterolemia (FH) is an autosomal dominant disorder that causes severe elevations in total cholesterol and low-density lipoprotein cholesterol (LDLc).
		The family history is usually significant for premature CAD or severe hypercholesterolemia in both parents and in second-degree paternal and maternal relatives.
		The NCEP recommendations for the dietary management of hypercholesterolemia are not highly restrictive, but a more stringent regimen may have a greater impact on lipid levels (see Table 2).
	www.emedicine.com /med/topic1072.htm (7452 words)

	Hypercholesterolemia
		Cholesterol is a soft waxy substance that is a natural component of the fats in the bloodstream and in all the cells of the body.
		While cholesterol is an essential part of a healthy body, high levels of cholesterol in the blood (known as hypercholesterolemia) increase a person's risk for cardiovascular disease, which can lead to stroke or heart attack.
		Those being treated for hypercholesterolemia should have their cholesterol levels measured every 2 to 6 months and have liver function tests as well if they are on cholesterol-lowering medication.
	www.umm.edu /altmed/ConsConditions/Hypercholesterolemiacc.html (6423 words)

	The fetal origins of atherosclerosis: maternal hypercholesterolemia, and cholesterol-lowering or antioxidant treatment ...
		of maternal hypercholesterolemia and the involvement of oxidative
		Evidence for the causal role of maternal hypercholesterolemia and lipid oxidation in accelerated postnatal atherogenesis.
		that in the absence of postnatal hypercholesterolemia, significant
	www.fasebj.org /cgi/content/full/16/11/1348 (6535 words)

	Dietary Therapy for Children with Hypercholesterolemia - February 1, 2000 - American Academy of Family Physicians
		In persons with familial hypercholesterolemia, there is a direct association between the duration and severity of hypercholesterolemia and extravascular lipid deposition in tissues.
		Parental hypercholesterolemia is defined as a total blood cholesterol level of 240 mg per dL (6.20 mmol per L) or higher.
		In a child with a high cholesterol level (total cholesterol or LDL cholesterol), screening tests for secondary causes of hypercholesterolemia (in particular, diabetes and diseases of the thyroid, liver and kidney) should be performed.
	www.aafp.org /afp/20000201/675.html (3548 words)

	SparkNotes: Lipids and Coronary Heart Disease: Familial Hypercholesterolemia
		Homozygous familial hypercholesterolemia occurs at a rate of less than 1 in 1,000,000.
		The heterozygous form is characterized by marked (2-3x normal) elevations of LDL cholesterol and premature atherosclerosis that typically manifests itself in the fourth decade of life.
		Clinical clues to the presence of this disorder include a strong family history of early atherosclerotic cardiovascular disease, a family history of familial hypercholesterolemia, and physical evidence of lipid deposition, including tendon xanthomata, xanthelasma, and corneal arcus.
	www.sparknotes.com /health/lipids/section6.rhtml (250 words)

	Exercise attenuates the effects of hypercholesterolemia on endothelium-dependent relaxation in coronary arteries from ... (Site not responding. Last check: 2007-11-06)
		Exercise attenuates the effects of hypercholesterolemia on endothelium-dependent relaxation in coronary arteries from adult female pigs -- Woodman et al.
		Hypercholesterolemia impairs endothelium-dependent relaxations to aggregating platelets in porcine iliac arteries.
		Hypercholesterolemia causes generalized impairment of endothelium-dependent relaxation to aggregating platelets in porcine arteries.
	jap.physiology.org /cgi/content/full/96/3/1105 (4319 words)

	Familial hypercholesterolemia definition - Cholesterol: health and medical information about high cholesterol and heart ...
		Persons with familial hypercholesterolemia can reduce their risk by adhering to a very low cholesterol diet under a doctor's supervision, and may also need to take medications such as the statins that reduce their cholesterol level.
		Familial hypercholesterolemia is usually due to a genetic defect in the receptor for LDL (low density lipoprotein).
		They include type B hypercholesterolemia which is caused by ligand-defective apolipoprotein B-100 (APOB); and autosomal dominant hypercholesterolemia 3 (HCHOLA3) which is caused by mutation in the PCSK9 gene.
	www.medterms.com /script/main/art.asp?articlekey=3382 (344 words)

	Medical Dictionary: Hypercholesterolemia - WrongDiagnosis.com
		Hypercholesterolemia: the presence of an abnormal amount of cholesterol in the cells and plasma of the blood; associated with the risk of atherosclerosis
		Hypercholesterolemia: Hypercholesterolemia is listed as a type of (or associated with) the following medical conditions in our database: Blood conditions, Under-diagnosed conditions, Silent conditions
		Hypercholesterolemia: Cholesterol is a fatty substance produced by the liver to help meet the body’s need for hormones and bile acids.
	www.wrongdiagnosis.com /medical/hypercholesterolemia.htm (372 words)

	MedlinePlus Medical Encyclopedia: Familial hypercholesterolemia
		The outcome is likely to be poor in people with the homozygote type of familial hypercholesterolemia because it causes early heart attacks and is resistant to treatment.
		The outcome of other types of familial hypercholesterolemia depends in part on the patient's compliance with treatment, but reduction in serum cholesterol levels can be achieved and may be significant in delaying a heart attack.
		Families with a history of familial hypercholesterolemia may benefit from counseling, especially if both parents are affected.
	www.nlm.nih.gov /medlineplus/ency/article/000392.htm (892 words)

	Hypercholesterolemia (Site not responding. Last check: 2007-11-06)
		A blood specimen is obtained after the patient does not eat or drink anything (except water) for 12 hours.
		The reason for treating elevated cholesterol is to reduce an individual's risk of complications.
		People with hypercholesterolemia are at high risk of dying from heart disease.
	www.healthatoz.com /healthatoz/Atoz/ency/hypercholesterolemia.jsp (1696 words)

	Compound Heterozygous Familial Hypercholesterolemia and Familial Defective Apolipoprotein B-100 Produce Exaggerated ...
		The proband was a compound heterozygote for FH and FDB.
		Common mutations in the low-density-lipoprotein-receptor gene causing familial hypercholesterolemia in the Japanese population.
		Mutation analysis in familial hypercholesterolemia patients of different ancestries: identification of three novel LDLR gene mutations.
	www.clinchem.org /cgi/content/full/47/3/438 (2825 words)

	Perceived Vulnerability to Heart Disease in Patients with Familial Hypercholesterolemia: A Qualitative Interview Study ...
		Perceived Vulnerability to Heart Disease in Patients with Familial Hypercholesterolemia: A Qualitative Interview Study -- Frich et al.
		Familial hypercholesterolemia is caused by a defect in the gene
		hypercholesterolemia is caused by a single-gene mutation, which
	www.annfammed.org /cgi/content/full/4/3/198 (3416 words)

	Monogenic hypercholesterolemia: new insights in pathogenesis and treatment -- Rader et al. 111 (12): 1795 -- Journal of ...
		in the historic linkage of hypercholesterolemia to atherosclerosis.
		Autosomal recessive hypercholesterolemia (ARH) is a putative adaptor protein that is involved in the mechanics of LDLR-mediated endocytosis.
		The J.D. mutation in familial hypercholesterolemia: amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors.
	www.jci.org /cgi/content/full/111/12/1795 (5275 words)

	Severe Hypercholesterolemia, Impaired Fat Tolerance, and Advanced Atherosclerosis in Mice Lacking Both Low Density ...
		Severe Hypercholesterolemia, Impaired Fat Tolerance, and Advanced Atherosclerosis in Mice Lacking Both Low Density Lipoprotein Receptor-related Protein 5 and Apolipoprotein E -- Magoori et al.
		In the present study, we show extreme hypercholesterolemia in mice lacking both apoE and LRP5.
		Heterozygous mutation of ataxia-telangiectasia mutated gene aggravates hypercholesterolemia in apoE-deficient mice
	www.jbc.org /cgi/content/full/278/13/11331 (4051 words)

	Hypercholesterolemia \| AHealthyMe.com
		You are here: Home > Health A to Z > Hypercholesterolemia
		Persons with hypercholesterolemia are at high risk of dying from heart disease.
		"Hypercholesterolemia in children." Israel Medical Association Journal 2(10): 767-771, 2000.
	www.ahealthyme.com /topic/topic103549505 (1508 words)

	Adult Health Advisor 2005.4: High Cholesterol (Hypercholesterolemia)
		You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition.
		Hypercholesterolemia is a condition in which the level of cholesterol in your blood is high.
		When you have too much cholesterol, deposits of fat in the blood called plaque form inside blood vessel walls.
	www.med.umich.edu /1libr/aha/aha_hyc_crs.htm (870 words)

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