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Topic: Left ventricular hypertrophy


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In the News (Thu 17 Dec 09)

  
  Left ventricular hypertrophy - Wikipedia, the free encyclopedia
Left ventricular hypertrophy (LVH) is the abnormal thickening of the myocardium (muscle) of the left ventricle of the heart.
Primary disease of the muscle of the heart that cause LVH are known as hypertrophic cardiomyopathies.
Normal thickness of the left ventricular myocardium is from 0.6 to 1.1 cm (as measured at the very end of diastole.
en.wikipedia.org /wiki/Left_ventricular_hypertrophy   (344 words)

  
 Atlas of Pathology   (Site not responding. Last check: 2007-10-20)
Hypertrophy of the left ventricle is defined as a wall thickness greater than 1.5 cm.
When referring to an organ, hypertrophy means increased size of the organ and may be due to hypertrophy and/or hyperplasia (if the cells of the organ are capable of mitosis) of individual cells.
Hypertrophy and hyperplasia are forms of adaptation and are thus reversible.
www.med.uiuc.edu /PathAtlasf/Atlas02.html   (138 words)

  
 Left Ventricular Hypertrophy
LV hypertrophy is a powerful predictor of morbidity and mortality from myocardial infarction, stroke, and congestive heart failure [38, 39].
LV hypertrophy is a common disorder, occurring in 16% of Whites, 21% of American Indians and 33 to 43% of African-Americans [40, 41].
LV hypertrophy prevalence is particularly elevated in hypertensives, ranging from 22 to 60% [42], and varies by race [43].
www.sph.uth.tmc.edu /hgc/fbpp/techSigLVH.htm   (1453 words)

  
 UpToDate Electrocardiographic diagnosis of left ventricular hypertrophy
Left ventricular hypertrophy (LVH) refers to an increase in the size of myocardial fibers in the main cardiac pumping chamber.
The major conditions associated with left ventricular volume overload are aortic or mitral valve regurgitation and dilated cardiomyopathy.
Ventricular septal defects cause both right and left ventricular volume overload, while hypertrophic cardiomyopathy is an example of an inherited condition in which LVH (usually with asymmetric septal hypertrophy) occurs in the absence of any apparent hemodynamic pressure or volume overload.
patients.uptodate.com /topic.asp?file=ecgs/8021   (399 words)

  
 UpToDate Clinical implications and treatment of left ventricular hypertrophy in hypertension
LVH diagnosed by echocardiography, which is much more sensitive than the ECG [14], also carries an increased risk for cardiac events (angina and myocardial infarction, heart failure, and serious ventricular arrhythmia) and cardiovascular deaths [7,10,12,15,16].
After adjustment for other risk factors, LVH was associated with an increase in cardiovascular events (relative risk 2.08); for each 39 g/m2 increase in left ventricular mass there was a 40 percent increased risk of a major cardiovascular event (show figure 2).
The prevalence of left ventricular hypertrophy was 22 percent and the risk factor adjusted hazard ratio for sudden death was 2.16 (p = 0.008).
patients.uptodate.com /topic.asp?file=hyperten/20309   (1036 words)

  
 eMedicine - Hypertensive Heart Disease : Article by Kamran Riaz, MD
LVH, defined as an increase in the mass of the left ventricle (LV), is caused by the response of myocytes to various stimuli accompanying elevated BP.
Thus, the development of LVH is characterized by myocyte hypertrophy and by an imbalance between the myocytes and the interstitium of the myocardial skeletal structure.
Left ventricular hypertrophy: The development of LVH is clearly related to an increase in the cardiovascular mortality rate.
www.emedicine.com /med/topic3432.htm   (8987 words)

  
 Diovan Reduces Left Ventricular Hypertrophy   (Site not responding. Last check: 2007-10-20)
Moreover, left ventricular mass index (LVMI), an indicator of LVH, was reduced to a statistically significantly greater level with Diovan than with atenolol.
Left ventricular hypertrophy is commonly observed in patients with hypertension, and is a predictive factor for cardiovascular disease.
LVH is independent of other cardiovascular disease risk factors such as smoking and elevated plasma cholesterol levels.
www.pslgroup.com /dg/2F89E.htm   (953 words)

  
 ANBP2 Left Ventricular Hypertrophy Sub-Study   (Site not responding. Last check: 2007-10-20)
The Left Ventricular Hypertrophy (LVH) sub-study is being conducted in parallel with the main study, the participating randomised patients undergo an echocardiogram before commencing antihypertensive medication.
The aim of the sub-study is to determine the association of LVH, identified by echocardiography, with morbidity and mortality from cardiovascular events.
The LVH sub-study has the objective to be community based, therefore echocardiography is conducted in a semi-mobile manner at various sites, which are conveniently located to recruited patients.
www.health.adelaide.edu.au /ANBP2/lvhss.htm   (391 words)

  
 Left ventricular hypertrophy in adolescents with elevated blood pressure: assessment by chest roentgenography, ...
Left ventricular hypertrophy in adolescents with elevated blood pressure: assessment by chest roentgenography, electrocardiography, and echocardiography -- Laird and Fixler 67 (2): 255 -- Pediatrics
The purpose of this study was to assess the prevalence of left ventricular
prevalence of left ventricular hypertrophy and that echocardiography is the
pediatrics.aappublications.org /cgi/content/abstract/67/2/255   (457 words)

  
 OhioLINK ETD: Mitsnefes, Mark
The prevalence of LVH increased with each measurement: 57% at the initiation of the dialysis, 64% prior to and 71% after transplantation.
There was no significant change in the prevalence of concentric LVH during the study (36%, 21%, 21% for echo 1, 2, and 3 respectively).
The prevalence of eccentric LVH doubled in post-transplant patients compared to the first echocardiographic study (21%, 43%, and 50% for echo 1, 2, and 3 respectively).
rave.ohiolink.edu /etdc/view?acc_num=ucin990460568   (370 words)

  
 Effect of left ventricular hypertrophy on the cardiac electrical field: The concept of specific potential of myocardium
Electrocardiographic diagnostics of left ventricular hypertrophy is based on so-called voltage criteria, the increased amplitude of the QRS complex.
Left ventricular size is used as a denominator, taking into account the influence of left ventricular size on the voltage magnitude.
Changes in possible factors influencing QRS amplitude are not linear to increases in left ventricular mass, and the changes differ in different stages of experimental left ventricular hypertrophy.
www.pulsus.com /europe/03_03/bach_ed.htm   (339 words)

  
 CHEST: Left ventricular hypertrophy is a common echocardiographic abnormality in severe obstructive sleep apnea and ...   (Site not responding. Last check: 2007-10-20)
Left ventricular hypertrophy (LVH) is a leading cause of morbidity and mortality.
An increase in left ventricular mass predicts a higher incidence of clinical events, including death, attributable to cardiac disease.
The adverse cardiac consequences from LVH are likely ultimately related to coronary ischemia, with increased muscle mass that is inadequately perfused, and which may compress endocardial capillaries.
www.findarticles.com /p/articles/mi_m0984/is_2_124/ai_107395153   (1272 words)

  
 Echocardiographic differentiation of pathological and physiological left ventricular hypertrophy -- Hildick-Smith and ...
Left ventricular hypertrophy is a serious condition, strongly associated with the development of coronary artery disease,
Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and impact of overweight.
Left ventricular mass as determined by magnetic resonance imaging in male endurance athletes.
heart.bmjjournals.com /cgi/content/full/85/6/615   (2976 words)

  
 Blood pressure and myocardial infarction Low blood pressure can be hazardous -- Cruickshank et al. 308 (6939): 1301 -- ...
Cruickshank JM, Polese A. Left ventricular hypertrophy and the possible harmful effect of diastolic blood pressure.
Polese A, De Cesare N, Montorsi P. Upward shift of the lower range of coronary flow autoregulation in hypertensive patients with hypertrophy of the left ventricle.
Collins P, Cruickshank JM, Keegan J, Fox K. Acute blood pressure reduction causes an impairment of left ventricular function in hypertensive patients with coronary heart disease and left ventricular hypertrophy.
bmj.bmjjournals.com /cgi/content/full/308/6939/1301/a   (903 words)

  
 Left Ventricular Hypertrophy
A typical M-mode echocardiogram of left ventricular hypertrophy is shown in (Fig.
In the majority of instances, left ventricular hypertrophy causes equal thickening of both the septum and the posterior wall.
In perhaps 10% of cases, left ventricular hypertrophy may manifest on echocardiograms in an asymmetric form with the septum thicker than the posterior wall but without other stigmata of hypertrophic cardiomyopathy.
www.echoincontext.com /int2/skillI2_02.asp   (765 words)

  
 Influence of hypertension, left ventricular hypertrophy, and left ventricular systolic dysfunction on plasma N terminal ...
Left ventricular mass was calculated using the equation described by Devereux and Reichek.
LVH is known to be an independent risk factor for all the cardiovascular complications of hypertension.
Cross-sectional echocardiographic analysis of the extent of left ventricular asynergy in acute myocardial infarction.
heart.bmjjournals.com /cgi/content/full/83/3/278   (3083 words)

  
 Left ventricular hypertrophy - MayoClinic.com   (Site not responding. Last check: 2007-10-20)
Hypertrophy is enlargement of an organ or body part due to an increase in the size of its cells.
Left ventricular hypertrophy is thickening of the wall of the left pumping chamber of the heart.
Left ventricular hypertrophy is thickening of the wall of the left...
www.mayoclinic.com /invoke.cfm?id=HQ01033   (236 words)

  
 Left Ventricular Hypertrophy-Description   (Site not responding. Last check: 2007-10-20)
Left ventricular hypertrophy (LVH) is a condition wherein the cardiac muscle responds to increased resistance in the circulation by becoming enlarged, much as you would expect any muscle to do when challenged by 'exercise'.
Left ventricular hypertrophy is not just a sign of another disease process, but rather it is an independent predictor of disease in itself.
Left ventricular hypertrophy in hypertension - general and local trends in diagnosis and therapy.
www.musc.edu /bmt737/Spr_1999/russell/general.html   (280 words)

  
 Diabetes Care: Electrocardiographic left ventricular hypertrop... @ HighBeam Research   (Site not responding. Last check: 2007-10-20)
In the general population, left ventricular hypertrophy (LVH), either defined by echocardiographic or electrocardiogram (ECG) criteria, is strongly predictive of cardiovascular events, independent of conventional risk factors (1-3).
In the general population, LVH causes electrical heterogeneity in the heart (6) and is associated with sudden cardiac death secondary to ventricular arrhythmias.
This is consistent with previous studies suggesting the association between insulin resistance and LVH in both hypertensive subjects (18) and type 1 diabetic patients with nephropathy (4,5) and extends previous observations to normoalbuminuric subjects.
highbeam.com /library/doc0.asp?docid=1G1:136070790&refid=ink_tptd_mag   (1869 words)

  
 Hemodynamics and other determinants in development of left ventricular hypertrophy.   (Site not responding. Last check: 2007-10-20)
Evidence is abundant supporting the premise that left ventricular hypertrophy in hypertension is related primarily to the hemodynamic factor of the increased left ventricular afterload associated with the disease.
However, evidence is rapidly accumulating that additional, nonhemodynamic factors are associated not only with development of left ventricular hypertrophy but also with its regression that is related to antihypertensive therapy.
Precisely how each factor is translated into the biochemical events associated with development of hypertrophy remains to be clarified, as do the explanatory mechanisms of why certain depressor agents produce regression of ventricular hypertrophy, whereas other agents with more salutary hemodynamic effects do not.
www.arclab.org /medlineupdates/abstract_6222919.html   (177 words)

  
 Lars Erickson - Left Ventricular Hypertrophy
Left ventricular hypertrophy (LVH) means that the muscle of the left pumping chamber of the heart (left ventricle) is thickened.
The left ventricle's job is to pump blood to the body, and conditions that increase the work the left ventricle has to do can lead to thickening of the muscle.
If there is any concern about whether a child with LVH on ECG actually has a heart problem, the usual next step would be to consider a consultation with a pediatric cardiac specialist and usually an ultrasound of the heart (echocardiogram).
www.larserickson.com /PatientInfo/LVH.htm   (244 words)

  
 British Journal of Pharmacology - Abstract of article: Modification of left ventricular hypertrophy by chronic etomoxir ...
Etomoxir (2[6(4-chlorophenoxy)hexyl]oxirane-2-carboxylate), an irreversible carnitine palmitoyltransferase 1 inhibitor, reduces the expression of the myocardial foetal gene programme and the functional deterioration during heart adaption to a pressure-overload.
Transformation of pressure values to ventricular wall stress data revealed an improved myocardial function which could partially account for the enhanced function of the whole left ventricle.
The co-ordinated action of etomoxir on ventricular mass, geometry and myocardial phenotype enhanced thus the pressure generating capacity of hypertrophied pressure-overloaded left ventricles and delayed the deleterious dilative remodelling.
www.nature.com /bjp/journal/v126/n2/abs/0702312a.html   (372 words)

  
 REGRESSION OF LEFT VENTRICULAR HYPERTROPHY BY MOXONIDINE*   (Site not responding. Last check: 2007-10-20)
The present studies were performed to investigate the mechanisms involved in left ventricular regression by moxonidine.
Furthermore, in 60 µg-treated rats, ventricular DNA fragmentation was maximally increased at 1 and 2 weeks to 217% and 138% then decreased to 67% of untreated SHR, values not different from normotensive rats.
This study demonstrates that moxonidine treatment results in regression of left ventricular hypertrophy through stimulating apoptosis (cell death), as evidenced by reduced DNA content and increased DNA fragmentation.
www.pulsus.com /ccc2003/abs/a362.htm   (234 words)

  
 Re: Left Ventricular Hypertrophy
Left ventricular hypertrophy (LVH) is an enlargement of the left pumping chamber of the heart and may be due to several different things.
Athletic hypertrophy is usually less than this thickness and will return to normal size with cessation of the activity.
HOCM may be diagnosed in the absence of other causes of LVH and with the presence of a family history.
www.medhelp.org /perl6/cardio/archive/2327.html   (629 words)

  
 Left Ventricular Hypertrophy in the Renal Patient -- MIDDLETON et al. 12 (5): 1079 -- Journal of the American Society ...
Left Ventricular Hypertrophy in the Renal Patient -- MIDDLETON et al.
Left ventricular mass is calculated by assuming that the ventricle
and EDD is the end-diastolic diameter of the left ventricle.
jasn.asnjournals.org /cgi/content/full/12/5/1079   (3585 words)

  
 Amazon.ca: Books: Left Ventricular Hypertrophy   (Site not responding. Last check: 2007-10-20)
LVH is a highly important risk factor associated with major cardiovascular events, including symptomatic heart failure, particularly in patients with systemic hypertension.
A variety of noninvasive methods has emerged for detecting LVH and the assessment of reversal of hypertrophy, yet a lot of controversy remains about the connotations and clinical implications of LVH.
Left Ventricular Hypertrophy - Physiology versus Pathology is a bibliographical reflection of a Boerhaave Symposium held on April 9, 1999, in Leiden, The Netherlands.
www.amazon.ca /exec/obidos/ASIN/0792360389   (428 words)

  
 News - Irbesartan Improves Cardiac Repolarization In Hypertensive Left Ventricular Hypertrophy
Results are from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation Versus Atenolol (SILVHIA) and are reported by investigators from the Karolinska Institute in Stockholm, Sweden.
Repeat echocardiography and evaluation of QT dispersal, a reflection of cardiac repolarization heterogeneity, were performed on all patients and on 37 matched hypertensive controls without left ventricular hypertrophy.
Left ventricular mass was found to be related to QT dispersal.
www.docguide.com /news/content.nsf/news/8525697700573E1885256C7700613F51   (463 words)

  
 Not all left ventricular hypertrophy is created equal -- Klingbeil and Schmieder 14 (12): 2803 -- Nephrology Dialysis ...
Left ventricular hypertrophy: an independent determinant of survival in end stage renal failure.
Left ventricular hypertrophy and geometric remodeling in hypertension: stimuli, functional consequences and prognostic implications.
The prognostic importance of left ventricular geometry in uremic cardiomyopathy.
ndt.oxfordjournals.org /cgi/content/full/14/12/2803   (1321 words)

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