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Topic: Mesocortical pathway


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In the News (Fri 11 Dec 09)

  
 Antipsychotic - Wikipedia, the free encyclopedia
receptors in the dopamine pathways in the brain, so the normal effect of dopamine release in the relevant synapses is reduced.
receptors in the mesolimbic pathway of the brain which is thought to produce the intended antipsychotic effect.
Typical antipsychotics are not particularly selective and also block the same receptors in the mesocortical pathway, tuberoinfundibular pathway and the nigrostriatal pathway.
en.wikipedia.org /wiki/Antipsychotics   (1754 words)

  
 Dopamine
As a member of the catecholamine family, dopamine is a precursor to epinephrine (adrenaline) and norepinephrine (noradrenaline) in the biosynthetic pathways for these neurotransmitters.
Shortage of dopamine, particularly the death of dopamine neurons in the nigrostriatal pathway, causes Parkinson's disease, in which a person loses the ability to execute smooth, controlled movements.
This theory is often discussed in terms of drugs (such as cocaine and amphetamines), which seem to be directly or indirectly related to the increase of dopamine in these areas, and in relation to neurobiological theories of chemical addiction, which argue that these dopamine pathways are pathologically altered in addicted persons.
www.brainyencyclopedia.com /encyclopedia/d/do/dopamine.html   (1536 words)

  
 dopamine   (Site not responding. Last check: 2007-11-01)
Thus, shortage of dopamine, particularly the death of dopamine neurons in the nigrostriatal pathway, is a cause of Parkinson's disease, in which a person loses the ability to execute smooth, controlled movements.
Dopamine neurons in the mesolimbic pathway are particularly associated these conditions.
This is partly due to the discovery of a class of drugs called the phenothiazines (which block dopamine D
encyclopedia.mysleepcenter.com /dopamine.htm   (397 words)

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