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Topic: Methylene


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In the News (Fri 25 Dec 09)

  
  Methylene blue - Wikipedia, the free encyclopedia
Methylene Blue, methylthionine chloride or 3,7-bis(dimethylamino)phenothiazin-5-ium chloride is a chemical compound used as a dye and medication for Gram's stain, Wright's stain, and Jenner's stain and the treatment of methemoglobinemia.
Methylene Blue is also used in aquaculture, particularly by tropical fish hobbyists, as a treatment for ich (Ichthyophthirius multifilis).
Methylene Blue should not be confused with another histology stain methyl blue.
en.wikipedia.org /wiki/Methylene_blue   (147 words)

  
 Encyclopedia: Methylene chloride   (Site not responding. Last check: 2007-11-06)
Methylene chloride was first prepared in 1840 by the French chemist Henri Victor Regnault, who isolated it from a mixture of chloromethane and chlorine that had been exposed to sunlight.
Industrially, methylene chloride is produced by reacting either methyl chloride or methane with chlorine gas at 400-500°C. At these temperatures, both methane and methyl chloride undergo a series of reactions producing progressively more chlorinated products.
Methylene chloride is the least toxic of the simple chlorohydrocarbons, but it is not without its health risks.
www.nationmaster.com /encyclopedia/Methylene-chloride   (434 words)

  
 Olympus MIC-D: Polarized Light Gallery - Methylene Blue
Actual staining material labeled as methylene blue is either aged or akalinized, and the pure substance appears to be a rather poor histological stain.
The salt, methylene blue thiocyanate, is used as a redox indicator in the sanitary monitoring of milk.
Methylene blue is sometimes used in surgey as a dye for parts of the body the medical team wishes to identify.
www.olympusmicro.com /micd/galleries/polarized/methyleneblue2.html   (461 words)

  
 EPA - Air Toxics Website - Methylene Chloride (Dichloromethane)
Methylene chloride is predominantly used as a solvent.
Methylene chloride is predominantly used as a solvent in paint strippers and removers; as a process solvent in the manufacture of drugs, pharmaceuticals, and film coatings; as a metal cleaning and finishing solvent in electronics manufacturing; and as an agent in urethane foam blowing.
Methylene chloride is also approved for use as a postharvest fumigant for grains and strawberries and as a degreening agent for citrus fruit.
www.epa.gov /ttn/atw/hlthef/methylen.html   (1405 words)

  
 Methylene blue -- Facts, Info, and Encyclopedia article   (Site not responding. Last check: 2007-11-06)
Methylene Blue, methylthionine chloride or 3,7-bis(dimethylamino)phenothiazin-5-ium chloride is a ((chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight) chemical compound used as a (A usually soluble substance for staining or coloring e.g.
Methylene Blue is also used in aquaculture, particularly by tropical fish hobbyists, as a treatment for (Click link for more info and facts about ich) ich (Ichthyophthirius multifilis).
Methylene Blue should not be confused with another (The branch of biology that studies the microscopic structure of animal or plant tissues) histology stain (Click link for more info and facts about methyl blue) methyl blue.
www.absoluteastronomy.com /encyclopedia/m/me/methylene_blue.htm   (208 words)

  
 Your Home:Methylene Chloride   (Site not responding. Last check: 2007-11-06)
Methylene chloride is a colorless, liquid VOC widely used in paint removers, furniture strippers, degreasing agents, and aerosol propellants; as a blowing agent in flexible urethane foams; as a process solvent in the manufacture of furniture, plastics, pharmaceuticals, and food products.
Carbon monoxide (CO) is the major byproduct of the metabolic breakdown of methylene chloride in the body.
Health problems caused by methylene chloride can either be acute, which occur immediately or within a few days of exposure, or they can be chronic, which are long-term health effects that might not show up for many years.
www.aerias.org /kview.asp?DocId=80&spaceid=1&subid=9   (685 words)

  
 ATSDR - MMG: Methylene Chloride
Methylene chloride is a combustible liquid, but its vapor is flammable only when present in relatively high concentrations (14% to 22% in air).
Methylene chloride is an important solvent in paint and varnish strippers and in degreasing agents.
Methylene chloride is metabolized in the liver, in part to carbon monoxide, which will produce elevated carboxyhemoglobin levels and decrease the oxygen-carrying capacity of the blood.
www.atsdr.cdc.gov /MHMI/mmg14.html   (4484 words)

  
 ATSDR - ToxFAQs™: Methylene Chloride
Methylene chloride is used as an industrial solvent and as a paint stripper.
Methylene chloride is mainly released to the environment in air.
Methylene chloride does not easily dissolve in water, but small amounts may be found in drinking water.
www.atsdr.cdc.gov /tfacts14.html   (980 words)

  
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Methylene chloride, administered to F344 male and female rats in their drinking water for 2 years, induced histological alterations of the liver at doses ò50 mg/kg/day; the no-observed- adverse effect level (NOAEL) for the study was 5 mg/kg/day (U.S. Based on these data, the U.S. calculated an oral RfD of 0.06 mg/kg/day for methylene chloride.
In inhalation studies with methylene chloride, cytoplasmic vacuolization and fatty infiltration of the liver and tubular degeneration and regenerative changes of the kidneys were observed in rats exposed continuously to 25 or 100 ppm of the chemical for 100 days (ATSDR 1993).
Rats exposed to 500 ppm methylene chloride, 6 hours/day, 5 days/week for 2 years developed multinucleated hepatocytes (the liver was not affected at 200 ppm), and increased hemosiderosis, cytomegaly, and cytoplasmic vacuolization of the liver after exposure to 1000 ppm, 6 hours/ day, 5 days/week for 2 years (ATSDR 1993).
www.epa.gov /opptintr/chemfact/s_dcm.txt   (3192 words)

  
 Methylene Chloride   (Site not responding. Last check: 2007-11-06)
Methylene chloride causes cancer in laboratory animals, and there is some other evidence that it may cause cancer in humans.
Methylene chloride belongs to a large class of chemicals called organic solvents, and it is used mostly to dissolve other substances.
The amount of methylene chloride in your blood or in the air that you exhale is a good measure of your recent exposure.
www.dhs.ca.gov /ohb/hesis/mecl2.htm   (2038 words)

  
 Eco-USA: Methylene chloride
Methylene chloride, also known as dichloromethane, is a colorless liquid that has a mild sweet odor, evaporates very quickly, and will not easily burn.
Methylene chloride is mainly released to the environment in air and to a lesser extent in water and soil, due to industrial and consumer uses.
Methylene chloride that is present in water is broken down slowly by reactions with other chemicals or by bacteria.
www.eco-usa.net /toxics/mecl.shtml   (1216 words)

  
 Methylene chloride (EHC 164, 1996, 2nd edition)
Methylene chloride is mainly released to the environment in air and, to a lesser extent, in water and soil.
Methylene chloride was degraded at a concentration of 200 µg/litre in the aqueous phase of natural sediment.
Methylene chloride was found in 98.4% of the samples; the average concentration was 14.1 µg/litre, with a range of 1.2-93.2 µg/litre.
www.inchem.org /documents/ehc/ehc/ehc164.htm   (12693 words)

  
 AFSCME Health and Safety Fact Sheet - Methylene Chloride (Dichloromethane)
Methylene chloride causes a variety of cancers in laboratory animals, including cancer of the lung, liver, breast, and salivary glands.
Methylene chloride may irritate the lungs, especially when used near heat (furnaces, welding, etc.) Repeated exposures may cause bronchitis with cough, phlegm, and/or shortness of breath.
Exposure to methylene chloride may cause heart disease or aggravate pre-existing heart disease and cause irregular heartbeat, rapid pulse, and heart palpitations.
www.afscme.org /health/faq-meth.htm   (1767 words)

  
 RAIS: Methylene Chloride (75-09-2)   (Site not responding. Last check: 2007-11-06)
Methylene chloride is not known to occur naturally; it is produced by hydrochlorination of methanol or chlorination of methane or methyl chloride.
Methylene chloride and formic acid were detected in the urine of humans exposed by inhalation to 100 or 200 ppm methylene chloride for 24 hours (DiVincenzo et al., 1972).
Oral LD values for methylene chloride of 2121 mg/kg for rats and 1987 mg/kg for mice indicate that the two species are similarly susceptible to the lethal effects of methylene chloride (ATSDR, 1989).
risk.lsd.ornl.gov /tox/profiles/methylch.shtml   (5312 words)

  
 Methylene - Wikipedia, the free encyclopedia
In chemistry, methylene is a divalent functional group CH derived formally from methane.
The name "methylene" is used for two types of groups:
in formaldehyde (can be named methylene oxide, but it is not used/recommended).
en.wikipedia.org /wiki/Methylene   (80 words)

  
 Safety and Health Topics: Methylene Chloride
Methylene chloride, also called dichloromethane, is a volatile, colorless liquid with a chloroform-like odor.
Methylene chloride is used in various industrial processes in many different industries including paint stripping, pharmaceutical manufacturing, paint remover manufacturing, metal cleaning and degreasing, and so forth.
OSHA considers methylene chloride to be a potential occupational carcinogen.
www.osha.gov /SLTC/methylenechloride   (92 words)

  
 American Converters Eliminates Methylene Chloride Based Adhesives - MnTAP
Methylene chloride acts as the adhesive’s carrier solvent, transporting the adhesive and keeping it from bonding until it is applied.
Methylene chloride based adhesive is applied to each component by either a spray gun or a mechanical roller.
If the company was to comply with the rule while continuing to use methylene chloride adhesives, programs for routine air monitoring and medical surveillance of affected employees would have to be implemented.
www.mntap.umn.edu /intern/projects/itam-p3.htm   (1469 words)

  
 [No title]
Methylene chloride can also be added to aerosol sprays or used to extract unwanted material from foods and beverages, such as coffee.
Effects of methylene chloride on human health and the environment depend on how much methylene chloride is present and the length and frequency of exposure.
Methylene chloride is not likely to cause environmental harm at levels normally found in the environment.
www.epa.gov /opptintr/chemfact/f_dcm.txt   (761 words)

  
 RAIS: Methylene Chloride (75-09-2)   (Site not responding. Last check: 2007-11-06)
In industry, methylene chloride is widely used as a solvent in paint removers, degreasing agents, and aerosol propellants; as a polyurethane foam-blowing agent; and as a process solvent in the pharmaceutical industry.
Methylene chloride is readily absorbed from the lungs, the gastrointestinal tract, and to some extent through the skin.
Studies of workers exposed to methylene chloride have not recorded a significant increase in cancer cases above the number of cases expected for nonexposed workers (Hearne et al., 1987; Ott et al., 1983a; Friedlander et al., 1978).
risk.lsd.ornl.gov /tox/profiles/methylch_c.shtml   (695 words)

  
 CPSC Urges Ventilation To Reduce Methylene Chloride Cancer Risk: Safety Alert   (Site not responding. Last check: 2007-11-06)
Methylene chloride has been shown to cause cancer in certain laboratory animals.
The CPSC staff is studying various substitutes for methylene chloride to evaluate the flammability and chronic hazards of those formulations.
If a product containing methylene chloride must be used indoors, even in a garage; open all windows and doors and use a fan to exhaust the air outside during application and drying.
www.cpsc.gov /cpscpub/pubs/5059.html   (246 words)

  
 METHYLENE CHLORIDE
Methylene chloride is used as a solvent, especially where high volatility is required.
Activities where exposure to methylene chloride is possible is in using paint strippers, working in laboratories, and parts degreasing.
Conveniently located washing facilities capable of removing methylene chloride shall be provided for all employees whose skin may come into contact with solutions containing 0.1 percent or greater methylene chloride.
www.des.umd.edu /compliance/factsheet/methylenechloride.html   (1182 words)

  
 Lab Safety Supply - EZ Facts Safety Info - Document #173, The Methylene Chloride Standard
Methylene chloride, also known as dichloromethane, is used in many types of industries, including paint stripping, metal cleaning and degreasing, and polyurethane foam production.
Because methylene chloride is such a health hazard, workers and safety and health advocates have been calling for a new safety standard to address the issue.
Records regarding exposure monitoring should include the dates and times the monitoring was done, name and critical information of the employee exposed to methylene chloride, the operation affected by the methylene chloride, number of samples taken, sampling methods used and type of personal protective equipment used.
www.labsafety.com /refinfo/ezfacts/ezf173.htm   (1871 words)

  
 MedlinePlus Drug Information: Methylene Blue (Systemic)   (Site not responding. Last check: 2007-11-06)
Methylene (METH-i-leen) blue is used to treat a condition called methemoglobinemia.
Methylene blue is also used as a dye to stain certain parts of the body before or during surgery.
Although there is no specific information comparing the use of methylene blue in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.
www.nlm.nih.gov /medlineplus/druginfo/uspdi/202703.html   (964 words)

  
 AFGE | Methylene Chloride
Exposure to methylene chloride has been shown to cause damage to the nervous system, heart, liver, and skin.
Methylene chloride is used to clean metal and plastic, as a vehicle for adhesives, and in the manufacture of foamed plastics.
Although the use of methylene chloride has been significantly reduced or even eliminated at many facilities over the years, exposure to methylene chloride vapors remains a health issue in the furniture and aircraft industries.
www.afge.org /Index.cfm?Page=MethyleneChloride   (205 words)

  
 Methylene Chloride
Methylene chloride is used as a solvent in many of ECU's research laboratories.
As of April 1997, Methylene chloride use is regulated by a revised OSHA standard (29 CFR 1910.1052), available at http://www.osha.gov.
Some of this toxicity is a result of methylene chloride being metabolized into carbon monoxide within the body.
www.ecu.edu /oehs/LabSafety/MethyleneChloride.html   (340 words)

  
 MedlinePlus Medical Encyclopedia: Methylene blue test
The methylene blue test is a test to determine the type of methemoglobinemia an affected person has, based on the responsiveness of blood methemoglobin to the administration of methylene blue (a dark green powder that can turn methemoglobin back into normal hemoglobin).
Most methemoglobinemia quickly responds to IV administration of methylene blue, and can be controlled by daily doses of oral methylene blue and ascorbic acid.
If the administration of IV methylene blue does not significantly lower blood levels of methemoglobin, then a rare form of hereditary methemoglobinemia is suspected.
www.nlm.nih.gov /medlineplus/ency/article/003412.htm   (603 words)

  
 Optical Absorption of Methylene Blue   (Site not responding. Last check: 2007-11-06)
Methylene Blue can be activated by light to an excited state which in turn activates oxygen to yield oxidizing radicals.
This spectrum was taken with a HP spectrophotometer using a 1 cm quartz cuvette filled with 10µM solution of Methylene Blue in Water by Scott Prahl.
Tabulated data for the extinction coefficeint of methylene blue versus wavelength.
omlc.bme.ogi.edu /spectra/mb   (228 words)

  
 Safety and Health Topics: Methylene Chloride - OSHA Standards
Exposures to methylene chloride are addressed in specific standards for maritime, construction, and general industries.
This instruction ensures uniform enforcement of the Occupational Exposure to Methylene Chloride Standard as amended in the Federal Register (September 22, 1998, pages 50711-50732), by setting enforcement policy, providing inspection guidelines, and clarifying and interpreting the regulatory text.
This letter concerns whether methylene chloride used as a solvent or bonding agent is covered by the "formulation of products" stay for the methylene chloride standard.
www.osha.gov /SLTC/methylenechloride/standards.html   (348 words)

  
 Champion-Expanding Encyclopedia   (Site not responding. Last check: 2007-11-06)
The exposure hazards of methylene chloride (dichloromethane) as an aerosol is investigated and commented upon.
The general reluctance of the embalming industry to seek reduced exposure alternatives to traditional embalming chemicals is remarked upon.
Acceptable low-impact, lowered exposure alternatives to both lead chromate and methylene chloride are elucidated and discussed.
www.champion-newera.com /encyclo.html   (2975 words)

  
 ipedia.com: Corrin Article   (Site not responding. Last check: 2007-11-06)
A corrin is a polyaromatic ring related to the porphyrin ring in hemoglobin, consisting of 4 pyrrole subunits, joined on opposite sides by a C-CH3 methylene link, on one side by a C-H methylene link, and with the two of the pyrroles joined directly.
Compared to a porphyrin, it is missing a bridging methylene group between a pair of pyrroles.
Because of the loss of the bridging methylene, they do not have a full aromatic character around the entire ring.
www.ipedia.com /corrin.html   (173 words)

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