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Topic: Reflux oesophagitis


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  Acid Reflux & Oesophagitis   (Site not responding. Last check: 2007-11-03)
Most cases of oesophagitis are due to reflux of stomach acid which irritates the inside lining of the oesophagus.
Gastro-oesophageal reflux disease (GORD) This is a general term which describes the range of situations - acid reflux, with or without oesophagitis and symptoms.
This is due to the refluxed acid irritating the windpipe.
www.tripdatabase.com /spider.html?itemid=254239   (1876 words)

  
 Antioxidant herbal extract may help prevent and treat reflux oesophagitis
Reflux oesophagitis occurs when the gullet becomes inflamed as a result of stomach acid being pushed upwards towards the throat (acid reflux).
The researchers experimentally induced reflux oesophagitis in 60 rats and subsequently examined tissue samples for signs of ulceration and/or healing.
The authors conclude that oxygen free radical damage is a major cause of reflux oesophagitis, and that antioxidants should be considered alongside acid suppressants as primary treatment.
www.eurekalert.org /pub_releases/2001-08/bsj-ahe081401.php   (362 words)

  
 Liver Cancer Acupuncture Chinese Herbal Medical Cure Centre Treatment-Infertility Treatment herbal herbs cure cured ...   (Site not responding. Last check: 2007-11-03)
Gastro-oesophageal reflux is a condition where the lower oesophageal sphincter (the muscular ring at the lower end of the oesophagus) is abnormally relaxed and allows the stomach's acidic contents to flow back or 'reflux' into the gullet (oesophagus).
Oesophagitis is inflammation of the inner lining of the oesophagus caused by repeated episodes of gastro-oesophageal reflux.
The trouble is caused by the faulty oesophageal sphincter, the muscular ring at the lower end of the oesophagus, near the diaphragm.
geocities.com /thetoleherbs/gastrol.html   (1888 words)

  
 Systematic review of PPI and H2A in Reflux oesophagitis
Reflux healing and maintenance seemed to be an important area, with good trials, and where a systematic review with economic evaluation was needed.
In Barrett's oesophagitis the normal whitish/grey squamous epithelium of the oesophagus is replaced by red columnar gastric epithelium in the lower oesophagus.
This means that for every three patients with reflux oesophagitis treated with a proton pump inhibitor, one more will have their oesophagitis healed who would not have done had they been treated with a histamine antagonist.
www.jr2.ox.ac.uk /bandolier/bandopubs/gordf/gord.html   (6397 words)

  
 [No title]   (Site not responding. Last check: 2007-11-03)
Figure 1 A photomicrograph of an oesophageal biopsy section from the inflamed oesophageal epithelium from a subject with reflux oesophagitis stained for PGP.
Usually the problem is caused by reflux oesophagitis, which is brought on by stomach acid that has moved up to the gullet.
Any relation or association between H pylori and oesophageal disease—that is, Barrett’s oesophagus, oesophageal cancer, reflux oesophagitis, gastro-oesophageal reflux disease.
www.lycos.com /info/reflux-oesophagitis.html?page=2   (358 words)

  
 Reflux oesophagitis [Feb 1997; 36-3]
Reflux happens commonly but infrequently in many people, and it does not cause major harm because the natural peristalsis of the oesophagus clears the refluxate back into the stomach.
In others where acid reflux from the stomach is persistent, the result is damage to the oesophagus causing symptoms or macroscopic oesophageal damage, and here gastro-oesophageal reflux disease (GORD) can be said to be present.
Endoscopic oesophageal damage is graded on a scale of 1-4 with increasing severity of damage.
www.jr2.ox.ac.uk /bandolier/band36/b36-3.html   (1618 words)

  
 [No title]   (Site not responding. Last check: 2007-11-03)
Reflux occurs commonly, but infrequently, in most people, and probably causes little harm because the natural movement (peristalsis) of the oesophagus clears the acid and food back into the stomach.
When acid reflux from the stomach is frequent and persistent, the result is damage to the lining of the oesophagus known as reflux oesophagitis or peptic oesophagitis.
A hiatus hernia, while commonly associated with reflux, is not essential for reflux to occur.
www.gastro.net.au /diseases/reflux.html   (298 words)

  
 Oxidative stress is more important than acid in the pathogenesis of reflux oesophagitis in rats -- Oh et al. 49 (3): ...
In the reflux oesophagitis control (group II) and ranitidine pretreated (group V) groups, oesophageal mucosa was almost denuded and moderate to severe degrees of inflammation replaced the submucosa of reflux oesophagitis.
In the reflux oesophagitis control and ranitidine pretreated groups, the oesophageal submucosa was almost replaced with inflammatory cell infiltrations in accordance with the occurrence of oesophageal ulcerations.
Implication of duodenogastric reflux in the pathogenesis of Barrett's esophagus.
gut.bmj.com /cgi/content/full/49/3/364   (4174 words)

  
 Impairment of Vagal Function in Reflux Oesophagitis   (Site not responding. Last check: 2007-11-03)
Autonomic nervous function in reflux oesophagitis was assessed by measuring the response of the lower oesophageal sphincter to abdominal compression, gastric secretory response to insulin-induced hypoglycaemia and pulse rate variability with respiration.
In 59 of 83 patients with reflux oesophagitis the sphincter response was subnormal, and this was commoner in older patients but was unrelated to the presence of a hiatal hernia.
During oesophageal acid perfusion, the onset of pain, but not that of disordered motility, was delayed in those with an abnormal sphincter response suggesting impairment of afferent autonomic function.
www.gerd.com /articles/abstracts/496.htm   (281 words)

  
 Pharmaceutical care - (6) Gastro-oesophageal reflux disease
While any patient with dyspepsia may have heartburn, the diagnosis of gastro- oesophageal reflux disease (GORD) requires symptoms of heartburn to be predominant, or for oesophagitis or acid reflux to be demonstrated (by endoscopy or oesophageal pH monitoring, respectively).
The prevalence of oesophagitis in the community is estimated to be approximately 2 per cent and is found in more than half of those patients who present to their doctor with GORD.
In most patients with reflux symptoms there is abnormally prolonged exposure of the distal oesophagus to acid and pepsin, although in some patients with normal levels of acid/pepsin, increased oesophageal sensitivity may provide an explanation for symptoms.
www.pharmj.com /Editorial/19990814/continuing_education/gord.html   (4956 words)

  
 Gastroesophageal reflux disease - Wikipedia, the free encyclopedia
Gastroesophageal Reflux Disease (GERD; or GORD when spelling oesophageal, the BE form) is defined as chronic symptoms or mucosal damage produced by the abnormal reflux of gastric contents into the esophagus
It is estimated that of the approximately 8 million babies born in the U.S. each year, upwards of 35% of them may have difficulties with reflux in the first few months of their life.
The upper part of the stomach is wrapped around the LES to strengthen the sphincter and prevent acid reflux and to repair a hiatal hernia.
en.wikipedia.org /wiki/Reflux_oesophagitis   (1927 words)

  
 Gastro-oesophageal reflux (acid reflux)
Long-standing oesophagitis may be complicated by the formation of scar tissue that contracts and results in a narrowing (stricture) in the affected part of the oesophagus.
A simple way to change that is to use a pillow under the mattress or to raise the head of your bed by 10cm (4 inches) with blocks or a house brick under the bed frame.
The symptoms of gastro-oesophageal reflux can resemble those of a peptic ulcer, chest pains (angina pectoris), muscle pains, back problems, constipation, irritable bowel syndrome, gallstones, pancreatic disease etc. These conditions will sometimes have to be ruled out before the diagnosis can be made.
www.netdoctor.co.uk /diseases/facts/gastrooesophagealreflux.htm   (1152 words)

  
 Reflux oesophagitis in adult coeliac disease: beneficial effect of a gluten free diet -- Cuomo et al. 52 (4): 514 -- Gut
Reflux oesophagitis in adult coeliac disease: beneficial effect of a gluten free diet -- Cuomo et al.
Reflux oesophagitis in adult coeliac disease: beneficial effect of a gluten free diet
Diversity in the oesophageal phenotypic response to gastro-oesophageal reflux: immunological determinants.
gut.bmj.com /cgi/content/full/52/4/514   (2395 words)

  
 Corpus gastritis is protective against reflux oesophagitis   (Site not responding. Last check: 2007-11-03)
Background-Gastric acid is important in the pathogenesis of reflux oesophagitis.
The presence of acute or chronic gastritis in the corpus was significantly correlated with either type of gastritis in other areas of the stomach, In a multivariate logistic regression, age, sex, smoking status, and the presence of chronic corpus gastritis all exerted a significant influence on the presence of reflux oesophagitis.
Conclusions-While infection with H pylori alone may not affect the occurrence of reflux oesophagitis, the development of chronic corpus gastritis seems to be protective.
www.gerd.com /articles/recent/abstracts/1929.htm   (245 words)

  
 Gastroesophageal Reflux Disease (GERD)
Gastroesophageal reflux disease (GERD) is a digestive disorder that affects the lower esophageal sphincter (LES) -- the muscle connecting the esophagus with the stomach.
Gastroesophageal reflux occurs when the LES is weak or relaxes inappropriately allowing the stomach's contents to flow up into the esophagus.
For chronic reflux and heartburn, the doctor may prescribe medications to reduce acid in the stomach.
www.webmd.com /content/article/6/1680_51289   (1678 words)

  
 DoctorSolve Blog: Acid Reflux Disease
Studies show reflux commonly occurs at these times as a result of LES relaxations caused by distention of the stomach with food.
Normally, the pressure exerted by your diaphragm and LES prevents reflux, but after the LES is pushed into the chest, the additive pressure of is decreased.
Difficulties breathing and suffering from hoarseness because the refluxed fluid irritates the larynx and respiratory tract.
www.doctorsolve.com /blog/2006/01/acid-reflux-disease.html   (1190 words)

  
 GERD (Gastroesophageal Reflux Disease) - acid reflux, oesophagitis, treatment, symptoms
The condition may be due to an abnormal mechanical working of the esophagus (where it enters the stomach) since it can normally squeeze itself together to act as a shut-off valve, or tap, to keep stomach contents out.
In severe cases of oesophagitis, the lining of the oesophagus may become ulcerated, leading to pain and possible narrowing due to scarring (making the swallowing of food and sometimes even liquids difficult).
In people with oesophagitis, there may be an increased risk of cancer of the esophagus.
www.patienthealthinternational.com /article/501772.aspx   (593 words)

  
 the GASTROLAB Image Gallery: Reflux Oesophagitis
This oesophagitis has caused an ulceration surrounding the distal oesophagus, causing a slight stenosis of the distal oesophagus.
Barret´s oesophagus is a complication of longstanding reflux disease.
Barret´s oesophagus is associated with a significant risk of malignant transformation, causing the oesophageal cancers seen after longstanding reflux disease.
www.gastrolab.net /mg004.htm   (85 words)

  
 H pylori infection and reflux oesophagitis -- Kountouras et al. 53 (6): 912 -- Gut
H pylori infection and reflux oesophagitis -- Kountouras et al.
Efficacy of trimebutine therapy in patients with gastroesophageal reflux disease and irritable bowel syndrome.
Prevalence of gastroesophageal reflux disease (GERD) in H. pylori-positive peptic ulcer disease and the impact of eradication therapy.
gut.bmjjournals.com /cgi/content/full/53/6/912   (670 words)

  
 Medical treatments for the maintenance therapy of reflux oesophagitis and endoscopic negative reflux disease
Gastro-oesophageal reflux disease (GORD) - reflux of stomach contents +/- bile into the oesophagus causing symptoms such as heartburn and acid reflux - is a common relapsing and remitting disease which often requires long-term maintenance therapy.
Patients with GORD may have oesophagitis (inflammation of the oesophagus) or a normal endoscopy (endoscopy negative reflux disease or ENRD).
For a maintenance dose of PPI (half of the standard dose) versus placebo, the RR for oesophagitis relapse was 0.46 (95% CI 0.38 to 0.57) and versus H2RAs the RR was 0.57 (95% CI 0.47 to 0.69).
www.cochrane.org /reviews/en/ab003245.html   (445 words)

  
 ABC of the upper gastrointestinal tract: Oesophagus: Heartburn -- de Caestecker 323 (7315): 736 -- BMJ
Oesophagitis refers to endoscopic or histological evidence of an acute inflammatory process in the oesophagus.
Both oesophageal and gastric factors affect the occurrence of reflux.
Duodenogastro-oesophageal reflux of bile may play a subsidiary role to that of gastric acid and pepsin in patients with an
www.bmj.com /cgi/content/full/323/7315/736   (2104 words)

  
 Fortnightly review: Treatment of gastro-oesophageal reflux disease in adults -- Galmiche et al. 316 (7146): 1720 -- BMJ
Since gastro-oesophageal reflux disease is primarily a motility disorder the use of prokinetics has an excellent rationale.
In patients with moderate or severe oesophagitis proton pump inhibitors are the mainstay of treatment.
Galmiche JP, Barthelemy P, Hamelin B. Treating the symptoms of gastro-oesophageal reflux disease: a double-blind comparison of omeprazole and cisapride.
bmj.bmjjournals.com /cgi/content/full/316/7146/1720   (2707 words)

  
 Reflux Oesophagitis
Heartburn, reflux, acid regurgitation - these are some of the words people use to describe the unpleasant symptoms associated with stomach acid finding its way into the gullet (or oesophagus).
Once a diagnosis of reflux is made the first step is to decrease acid entering the oesophagus.
If you remain unwell and the tests you have had indicate that reflux is the problem then in some cases surgery may be helpful.
www.riverviewendo.com.au /reflux.htm   (593 words)

  
 Clinical Trial: Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With ...
The purpose of the study is to verify superiority of the lafutidine group over the placebo group and non-inferiority to the famotidine group in terms of endoscopic healing rate of the patients with mild reflux oesophagitis.
In Japan it is reported that many patients with reflux oesophagitis are relatively mild and do not usually require strong treatment, and even H2 receptor antagonists are considered to demonstrate sufficient healing effects.
Comparisons: The endoscopic healing rate of lafutidine in the patients with mild reflux oesophagitis is compared to the rate of placebo and it is also compared to the rate of famotidine.
www.clinicaltrials.gov /ct/show/NCT00229424   (791 words)

  
 Upregulated eotaxin expression and T cell infiltration in the basal and papillary epithelium in cows' milk associated ...
Macroscopic diagnosis of reflux esophagitis: erosions or eosinophils?
Intraepithelial eosinophils: a new diagnostic criterion for reflux esophagitis.
Reflux esophagitis in infant and children: a report from the Working Group on Gastroesophageal Reflux Disease of the Euopean Society of Pediatric Gastroenterology and Nutrition.
adc.bmj.com /cgi/content/full/87/2/124   (3341 words)

  
 UEGW: Rabeprazole 20 mg Equivalent to Omeprazole 20 Mg in Healing Reflux Oesophagitis
Sacco and colleagues enrolled 549 patients with a mean age of 47.42 years and endoscopically-confirmed oesophagitis (Savary-Miller grade I to III) plus day and night-time heartburn (minimum 3-4 days per week, moderate to strong intensity).
At baseline, 70.31% of patients presented with oesophagitis for the first time while 26.9% were relapse patients.
On endoscopy, 69.22% of an original 560 patients enrolled had SM grade 1 oesophagitis, 24.23% had grade II, and 5.46% III (1.09% had grade 0 and were excluded).
www.docguide.com /dg.nsf/PrintPrint/CAC4E664B55E7E2C85256DD50058601F   (447 words)

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