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Topic: THC

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Article 58

Hashish

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	Tetrahydrocannabinol (Site not responding. Last check: 2007-11-02)
		(THC) is the active chemical in cannabis and is one of the oldest hallucinogenic drugs known.
		The mode of action of THC is still not properly understood, although it is known that of the two stereoisomers (mirror images), the (-)-form (the left-handed form of the molecule) is 10-15 times more potent than the (+)-form.
		Also, as THC increases the appetite and reduces the vomit response, it is starting to be used in the treatment of anorexia and other eating disorders.
	www.ch.ic.ac.uk /rzepa/mim/drugs/html/thc_text.htm (464 words)

	THC
		THC is the primary active ingredient `in every cannabis preparation, from marijuana to hashish to hash oil.
		THC is such an unstable subsance that it must be kept below freezing, in sealed glass vials, to retain its potency.
		THC causes an increased heart rate, reddening of the eyes, and a dry mouth resulting from reduced saliva flow.
	www.drugtext.org /library/books/recreationaldrugs/thc.htm (633 words)

	THC (TETRAHYDROCANNABINOL) ACCUMULATION IN GLANDS OF CANNABIS (CANNABACEAE)
		THC is present in the disc cell wall (W), subcuticular wall (large arrowhead), along the surface features around vesicles in the cavity (small arrowhead), in fibrillar matrix being released from the disc cell wall (open arrow) and in the cuticle (arrow).
		THC is abundant along the surface features (arrow) of the numerous vesicles in the secretory cavity, but absent from the content in the vesicles.
		THC accumulated in abundance in the secretory cavity where it was associated with the: a) cell walls, b) surface feature of secretory vesicles, c) fibrillar material released from disc cell wall, and d) cuticle.
	www.hempreport.com /issues/17/malbody17.html (5021 words)

	.:: The Hacker's Choice - THC ::. (Site not responding. Last check: 2007-11-02)
		THC is an acronym for 'The Hacker's Choice' and a group of international experts involved in network and system security.
		THC was founded in 1995 in Germany, has published over 60 software releases and technical papers and currently is among the top ten security groups worldwide.
		THC is a non-commercial group and all releases, papers and even this web site have been developed in the free time of the THC members.
	www.thc.org (393 words)

	THC Limits for Food, Part II
		With regard to THC limits in food, the data situation is fortunate, as the daily THC intake of chronic Cannabis consumers (50-200 mg or 1-3 mg/kg BW, respectively) already clearly exceeds the daily doses of relevance to this study (0.1-0.2 mg/kg) by a factor of 10-15.
		THC crosses the blood-brain barrier comparatively easily and accumulates in fatty tissues from where it is re-released only slowly into other tissues, such as the blood.
		The higher survival in the THC group was primarily due to a decreased incidence of cancer.
	www.hempfood.com /thclimits2a.html (6600 words)

	nova Institute: THC-Limits for Food PART 2 Section 5
		THC in doses used by marijuana smokers is neither mutagenic nor carcinogenic and it does not affect cell metabolism, either.
		THC was found to exert a biphasic effect on lymphocyte metabolism, with a stimulation at low doses and a suppression at high THC concentrations.
		THC treatment (10 or 15 mg/kg) during primary immune response caused a decrease in thymus weight and reduced the number of thymus cells.
	www.naihc.org /hemp_information/content/nova_report/part2b.html (9400 words)

	THC Project
		THC source code is available on a CVS source code repository which can only be accessed from the University of Utah (by the way, why are you reading this file if you're not from the U?).
		THC is supposed to be portable (at least on Linux/Irix, which are the two platforms I use).
		THC relies on third party Open Source toolkits, which are chosen for their use and portability.
	www.cs.utah.edu /~xavier/thc/install.html (442 words)

	Tetrahydrocannabinol - Wikipedia, the free encyclopedia
		THC has analgesic effects that, even at low doses, cause a "high", and cannabis was once commonly used to treat pain.
		THC receptor distribution in the rat CNS is different from that of humans, meaning that there is the significant possibility that toxicity in humans varies from the published animal LD studies.
		THC, the main active component in marijuana, may protect the brain from the ravages of Alzheimer's disease, U.S. scientists reported.
	en.wikipedia.org /wiki/Tetrahydrocannabinol (1160 words)

	Evaluating Interference of THC in Hemp Food Products
		The presence of THC in hemp foods has raised concern over their potential interference with employee drug-testing programs in the U.S. Studies conducted in 1995—1997 showed that eating hemp foods may in fact cause positive urine tests for marijuana.
		THC was consumed in 15 milliliter (mL) doses–equivalent to one tablespoon (0.6 mg in 20 mL)–of four different blends of hemp and canola oils.
		The table shows the daily THC doses administered during the study and the corresponding amounts of hemp oil and hulled seeds–containing 5 and 2 ppm THC, respectively–that would have to be eaten to ingest the same amounts of THC.
	www.naihc.org /hemp_information/content/THC_emp_drug_testing.html (1588 words)

	THC Synthesis - Overview
		The syntheses of THC-A, THC-B, or THC-C are all based on the condensation of olivetol (5-(n-amyl)-resorcinol) with a second component which forms the left-hand and center ring of the THC molecule.
		The THC containing an n-amyl side chain on the right-hand ring is identical to the active component of hashish or marihuana.
		The synthesis is as for THC, except that in method I pentanonitrile is replaced by hexanonitrile, while in method II 1-bromo-butane is replaced by an equivalent amount of 1-bromo-pentane.
	www.erowid.org /archive/rhodium/chemistry/thc (1114 words)

	Accu-Stat Diagnostics - Panel 1 Home Drug Test for Marijuana ( THC ) (Site not responding. Last check: 2007-11-02)
		The peak effect of smoking THC occurs in 20-30 minutes and the duration is 90-120 minutes after one cigarette.
		The Accu-Stat THC test is based on the principle of the highly specific immunochemical reactions between antigens and antibodies which are used for the analysis of specific substances in biological fluids.
		The accuracy of Accu-Stat THC was evaluated in comparison to a quantative laboratory test with agreement observed in 99% of the samples.
	www.accu-stat.com /details.asp?ProductID=1 (1365 words)

	Synthetic THC / Marinol (Site not responding. Last check: 2007-11-02)
		When THC is swallowed, the effects vary considerably, both from one person to the next and in the same person from one episode to another.
		In a study of elderly patients, the large dose of oral THC needed to reduce nausea and vomiting produced severe psychoactive effects, reducing its utility as a medicine.
		Still another failure of synthetic THC medications is their lack of the multiple ingredients which appear in natural marijuana.
	www.ardpark.org /reference/marinol.htm (521 words)

	Drugs and Human Performance FACT SHEETS - Cannabis / Marijuana ( D 9 -Tetrahydrocannabinol, THC)
		THC is highly lipid soluble, and plasma and urinary elimination half-lives are best estimated at 3-4 days, where the rate-limiting step is the slow redistribution to plasma of THC sequestered in the tissues.
		THC is rapidly and extensively metabolized with very little THC being excreted unchanged from the body.
		A majority of THC is excreted via the feces (~65%) with approximately 30% of the THC being eliminated in the urine as conjugated glucuronic acids and free THC hydroxylated metabolites.
	www.nhtsa.dot.gov /PEOPLE/INJURY/research/job185drugs/cannabis.htm (2524 words)

	BioMed Central \| Full text \| Delta-9 tetrahydrocannabinol (THC) inhibits lytic replication of gamma oncogenic ...
		The effect of THC on Kaposi's Sarcoma Associated Herpesvirus (KSHV) and Epstein-Barr virus (EBV) replication was measured by the Gardella method and replication of herpesvirus saimiri (HVS) of monkeys, murine gamma herpesvirus 68 (MHV 68), and herpes simplex type 1 (HSV-1) was measured by yield reduction assays.
		THC specifically targets viral and/or cellular mechanisms required for replication and possibly shared by these gamma herpesviruses, and the endocannabinoid system is possibly involved in regulating gamma herpesvirus latency and lytic replication.
		THC binds to and activates either one of the two cannabinoid receptors (CB1 and CB2) located on the surface of both brain and lymphoid cells [17-26].
	www.biomedcentral.com /1741-7015/2/34 (4982 words)

	THC Professional Audio Company - Leading designer and manufacturer of professional loudspeaker systems - approved by a ...
		THC Professional Audio Company - Leading designer and manufacturer of professional loudspeaker systems - approved by a large number major international performers.
		THC Ltd. will take place at the 2006 Prolight + Sound in Frankfurt - the world's biggest international trade fair for...
		THC Audio took place at the 2004 Prolight + Sound in Frankfurt - the world's biggest international trade fair for even...
	www.thcaudio.com (359 words)

	TEST INSTRUCTIONS: DRUG: Marijuana Drug Test THC Urine Cassette
		The one step THC (Tetrahydrocannabinol) test is a simple one step immunochromatographic assay for the rapid, qualitative detection of THC and its metabolites 11-nor- 9-tetrahydrocannabinol-9-carboxylic acid in urine.
		THC (9-tetrahydrocannabinol) is the primary active ingredient in cannabinoids (marijuana).
		The THC test is based on the principle of the highly specific immunochemical reactions between antigens and antibodies, which are used for the analysis of specific substances in urine.
	www.meditests.com /t-drug2.html (1642 words)

	Inhaled THC Produces Better Blood Levels than THC by Mouth
		It might be argued that the association of THC plasma concentrations to the incidence of nausea and vomiting is not causally related to an antiemetic effect of THC, but rather due to increased absorption of oral doses by the gastrointestinal tract in patients experiencing less nausea and vomiting from other causes.
		Similarly, elevations of THC plasma concentrations achieved primarily by the inhalation route were also associated with reductions in the incidence of nausea and vomiting.
		Some reduction in THC effectiveness may be attributable to the normal variation of nausea and vomiting responses in a patient observed for multiple courses and to the fact that only THC responders were studied in Phase II.
	www.medmjscience.org /Pages/science/chang.bhtml (4326 words)

	HOW DOES MARIJUANA AFFECT THE BRAIN?
		THC is the main active ingredient in marijuana because it affects the brain by binding to and activating specific receptors, known as cannabinoid receptors.
		THC also affects the production, release or re-uptake (a regulating mechanism) of various neurotransmitters."(2) Neurotransmitters are chemical messenger molecules that carry signals between neurons.
		"When THC attaches to receptors in the hippocampus, it weakness the short-term memory,"(5) and damages the nerve cells by creating structural changes to the hippocampus region of the brain.
	serendip.brynmawr.edu /bb/neuro/neuro04/web1/aejelonu.html (1515 words)

	Cyberbotanica: THC
		THC's intoxicating and medicinal properties have been touted for thousands of years; however, use of the substance is highly controlled in the U.S. and in some other countries.
		Possession of unprescribed THC is illegal in the U.S. and many other countries.
		Please send her e-mail or fill out a feedback form if you spot any errors in these pages, or if you have any suggestions or comments.
	biotech.icmb.utexas.edu /botany/thc.html (354 words)

	THC scientifically shown to shrink cancer tumors. (Site not responding. Last check: 2007-11-02)
		THC administration was ineffective in three rats, which died by days 16-18.
		Guzman's investigation is the only time since the 1974 Virginia study that THC has been administered to live, tumor-bearing animals.
		The summary of the Virginia study begins, "Lewis lung adenocarcinoma growth was retarded by the oral administration of tetrahydrocannabinol (THC) and cannabinol (CBN)" -- two types of cannabinoids, a family of active components in marijuana.
	www.ardpark.org /research/shrinktumors.htm (1026 words)

	Honolulu Star-Bulletin Features
		THC has been playing original reggae for years, and just released a new album, "Jah Music," but group spokesman Maakah says THC enjoys backing other artists for several reasons.
		THC is the senior Hawaii-based reggae band participating in the Bob Marley memorial concert at Blaisdell Arena on Saturday.
		THC sometimes has to rehearse using tapes in which the artist's own musicians wobble between keys.
	starbulletin.com /2000/03/02/features/story1.html (837 words)

	Marijuana and Cocaine 2 panel test
		THC is rapidly absorbed by inhalation or by the gastrointestinal tract, and is almost completely metabolized.
		Very low concentrations of THC may be detected in urine during the initial several hours, but THCA persists in urine at a detectable concentration for many days after smoking or other ingestion.
		The absence of a line in the THC test area is a positive test result for that drug.
	www.craigmedical.com /THC_COC_test.htm (1227 words)

	Marijuana May Thwart Pregnancy, THC May Hamper Fertilized Egg From Implanting In Womb - CBS News
		The THC group was least likely to have their eggs implant in the womb, the study shows.
		But when THC is present, it swoops down and nabs the prized parking spots, leaving anandamide circling aimlessly.
		As a result, the mice in the THC group were more likely to not have their fertilized egg implant in the womb, compared with the other mice, the study shows.
	www.cbsnews.com /stories/2006/08/01/health/webmd/main1857985.shtml (745 words)

	Rapid Marijuana THC tests
		Tetrahydrocannabinol (THC) is generally accepted to be the principle active component in marijuana, although other cannabinoids are likely to contribute to the physiological activity of marijuana.
		Very low concentrations of THC may be detected in urine during the initial several hours, but THCA persists in urine at a detectable concentration for many days after smoking.
		When THC levels are below 50 ng/ml (the detection cutoff sensitivity of the test) unbound antibody-dye conjugate binds to immobilized antigen conjugate in the Test Zone ("T"), producing a pink-rose colored band that indicates a negative result.
	www.craigmedical.com /marijuana.htm (1113 words)

	HON - News : Pot's Active Ingredient Could Fight Alzheimer's (Site not responding. Last check: 2007-11-02)
		In their work in the laboratory, the researchers found that THC inhibits a different site on the acetylcholinesterase molecule and at lower concentrations.
		They also discovered that THC prevents the formation of amyloid protein plaques that damage the brain and are a hallmark of Alzheimer's disease.
		In addition, THC may prove valuable as a model for developing new and more effective drugs to treat the disease, they said.
	www.hon.ch /News/HSN/535386.html (389 words)

	Tenderloin Housing Clinic
		THC operates both the Central City and Mission SRO Collaborative through a contract with the Department of Public Health.
		THC also operates a Tenant Representative program in order to enhance stability in the hotels and address residential community concerns.
		THC has obtained Redevelopment Agency funding at the Seneca to build a community kitchen and a laundry and to increase accessibility for disabled persons.
	www.thclinic.org (986 words)

	Marijuana as medicine: Consider the pros and cons - MayoClinic.com
		An abbreviation for delta-9-tetrahydrocannabinol, THC is the main component responsible for marijuana's mind-altering effect.
		When smoked or ingested, THC and other cannabinoids in marijuana attach to two types of receptors on cells in your body — like keys in a lock —; affecting the cells, once attached.
		In fact, THC may work as well in treating cancer pain as codeine, a mild pain reliever.
	www.mayoclinic.com /health/medical-marijuana/GA00014 (1281 words)

	Cannabis Ministry Amsterdam : Home : THC Ministry Amsterdam
		The Amsterdam THC Ministry, First Universal Church of Kantheism, is based on ancient wisdom, modern science and the enlightening and healing properties of the cannabis sacrament.
		The THC Ministry began in September of 2000 on Hawai'i, founded by Reverend Roger Christie and has provided cannabis Sanctuary paperwork to thousands of people to help protect the practice of cannabis spirituality everywhere.
		In 2005, a synergistic union between the Amsterdam THC Ministry and the First Universal Church of Kantheism was, at last, realized, in order to better serve those who walk the path of Cannabis Spirituality.
	www.thc-ministry.net /home.htm (523 words)

	Marijuana Antagonist Reveals Evidence of THC Dependence in Rats
		During his research, rats were exposed to THC for 4 days, then given a dose of the THC antagonist SR 141716A, which was developed by French scientists last year.
		The rats immediately and "dramatically" exhibited classic rodent behavioral withdrawal symptoms, indicating that they were dependent on THC, Dr. Martin said.
		The National Institute on Drug Abuse (NIDA) is part of the National Institutes of Health (NIH), a component of the U.S. Department of Health and Human Services.
	www.nida.nih.gov /Nida_Notes/NNVol10N6/THCRats.html (555 words)

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